Results 291 to 300 of about 160,587 (337)

Mechanisms of plaque stabilization with statins

The American Journal of Cardiology, 2003
The traditional view of cardiovascular disease held that the degree of stenosis defined high-risk lesions and that removal of cholesterol shrank these lesions and thereby enlarged the lumen. Advances in understanding of the pathophysiology of the acute coronary syndromes refute this view.
Peter, Libby, Masanori, Aikawa
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Atherosclerotic Plaque Stability—What Determines the Fate of a Plaque?

Progress in Cardiovascular Diseases, 2008
Although the understanding of the underlying pathology of atherosclerosis has improved in recent years, the disease is still the main cause of death globally. Current evidence has implicated the role of inflammation in atherogenesis and plaque destabilization.
Bente, Halvorsen, Kari, Otterdal, Tuva B, Dahl, Mona, Skjelland, Lars, Gullestad, Erik, Øie, Pål, Aukrust   +6 more
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Carotid Atherosclerotic Plaques Stabilize After Stroke

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009
Objective— Rupture of unstable atherosclerotic plaques is the pathological substrate for acute ischemic events. Underlying cellular and molecular characteristics of plaque rupture have been studied extensively.
W, Peeters, W E, Hellings, D P V, de Kleijn, J P P M, de Vries, F L, Moll, A, Vink, G, Pasterkamp   +6 more
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PATHOPHYSIOLOGY OF PLAQUE RUPTURE AND THE CONCEPT OF PLAQUE STABILIZATION

Cardiology Clinics, 1996
Atherosclerotic coronary artery disease is the major cause of death, in men and women, in the United States and in much of the Western world. Atherosclerosis is responsible for coronary heart disease, limb ischemia, and most strokes. Although luminal narrowing by an atherosclerotic plaque and exaggerated or anomalous vasoconstriction contribute to some
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Atherosclerotic plaque stabilization and regression

Vasa
Summary: Atherosclerotic plaques represent a typical deterioration of arterial wall in atherosclerotic process and are the source of cardiovascular events. Plaque progression and composition represent a major risk for cardiovascular events. Therefore, recently many studies have assessed changes in plaque characteristics and their response to various ...
Pavel Poredoš, Ana Spirkoska Mangaroska, Peter Poredoš   +2 more
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Can we stabilize unstable plaque?

Current Atherosclerosis Reports, 2003
From these considerations, successful therapeutic approaches should control multiple aspects of plaque stabilization. Statins fulfill such a requirement, yet combination therapy may be of use in specific clinical settings. Despite remarkable therapeutic achievements in the management of acute coronary syndromes, mortality rates for this disease ...
PAOLETTI R, CIGNARELLA, ANDREA
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Regression and stabilization of atherogenic plaques

Trends in Cardiovascular Medicine
Atherosclerotic plaque assessment has become a crucial element in the examination of cardiovascular diseases. Plaque may exhibit progression and could become unstable if not treated, making plaque regression and stabilization among the most important goals of any cardiovascular intervention in cardiovascular medicine.
Jairo Aldana-Bitar, Deepak L. Bhatt, Matthew J. Budoff   +2 more
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[Plaque stabilization by LDL apheresis?].

Herz, 1999
Vulnerable lipid-rich plaques are often the cause of atherothrombotic events leading to unstable angina and/or to acute myocardial infarction. Consequent long-term LDL-lowering by drugs as shown by the most important intervention studies lead to plaque stabilization as shown by the significant reduction of myocardial reinfarction.
P, Schuff-Werner, V, Schettler
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Stabilization of atherosclerotic plaque during lipid lowering

Current Opinion in Lipidology, 1997
Lipid lowering therapy leads to a great reduction of cardiovascular complications, but has almost no effect on the degree of stenosis of coronary arteries. These findings have lead to a new paradigm of coronary artery disease, i.e. clinical prognosis is not only determined by the extent of a single stenosis, but mainly by the number and structure of ...
D, Müller-Wieland, J, Kotzka, W, Krone
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[Mechanisms of plaque stabilization].

Herz, 1999
Numerous angiographic control regression studies have demonstrated that aggressive reduction of plasma cholesterol significantly reduces the incidence of clinical overt cardiovascular complications, but has almost no effect on the angiographically determined luminal diameter of the coronary arteries.
D, Müller-Wieland, M, Faust, J, Kotzka, W, Krone   +3 more
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