Results 131 to 140 of about 29,000 (256)

Single‐Cell RNA Sequencing Informs Precision Targeting of Monogenic Lupus Associated With IKZF1 Haploinsufficiency

Arthritis &Rheumatology, EarlyView.
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng, Yejun Tan, Zhaoling Wang, Yanjie Qian, Qian Ma, Danping Shen, Meiping Lu   +6 more
wiley   +1 more source

Molecular Dynamics Simulation of Passive Diffusion across a Human Breast Cancer Cell Membrane Model. Comparison between Cisplatin and Its Pt(IV) Derivatives. [PDF]

J Chem Inf Model
Belletto D, Scoditti S, Borocci S, Sanna N, Zazza C, Sicilia E.   +5 more
europepmc   +1 more source

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

Autism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni, Lisa Asta, Nicole Giompaolo, Rinvil Renaldi, Alberto Amaretti, Maddalena Rossi, Antonio M. Persico   +6 more
wiley   +1 more source

The self-assembly mechanisms of glycyrrhizic acid: Permeation enhancement and transdermal applications. [PDF]

Int J Pharm X
Zhou L, Deng Y, Ou M, Wang Z.
europepmc   +1 more source

Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders

Bulletin of the Korean Chemical Society, EarlyView.
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley   +1 more source

Advances in Insulin Delivery: Transdermal and Needle-Free Technologies as Emerging Strategies to Improve Metabolic Control and Treatment Adherence. [PDF]

Life (Basel)
García-Sáenz M, Gómez-Romero OJ, Espinosa-Cárdenas E, Ramírez-Rentería C, Doval-Caballero JLE, Uribe-Cortés D, Ferreira-Hermosillo A.   +6 more
europepmc   +1 more source

Hydrogen Isotopes Plasma-Driven Permeation through Tungsten Coated Reduced Activation Ferritic Steel F82H

Hydrogen Isotopes Plasma-Driven Permeation through Tungsten Coated Reduced Activation Ferritic Steel F82H
Hydrogen isotopes plasma-driven permeation (PDP) through F82H coated with two different types of tungsten coatings, i.e., sputter-deposited tungsten (SP-W) and vacuum plasma-sprayed tungsten (VPS-W) has been studied in the temperature range of 300 - 550 °C.
openaire  

Charakterisierung plasma-getriebener Permeation zur Entwicklung einer wasserstoffselektiven Vakuumpumpe = Characterization of plasma-driven permeation for the development of a hydrogen-selective vacuum pump

In thermonuklearen Fusionsreaktoren werden die beiden Wasserstoffisotope Deuterium und Tritium unter Energiefreisetzung zur Kernfusion gebracht. Der Verwendung von Tritium stehen globale Knappheit, die Radioaktivität des Isotops und die Eignung für den Einsatz in Kernwaffen gegenüber, welche mit strengen Lizensierungsauflagen durch Regulatoren ...
openaire   +3 more sources

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Ultradeformable Vesicles for Wound Healing: Ethosomes, Transferosomes, and Transethosomes in Topical Drug Delivery. [PDF]

Pharmaceutics
Jacob S, Varkey NR, Nair AB.
europepmc   +1 more source