Results 161 to 170 of about 29,000 (256)

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

Nanoformulation-Based Transdermal Drug Delivery: A Paradigm Shift in Antiparasitic Therapy for Zoonotic Diseases. [PDF]

Pharmaceutics
Zhao Y, Xiu R, Wang C, Wang J, Guo D, Luo W, Jiang S, Ge Z, Gao X.   +8 more
europepmc   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

Barrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu, Shih‐Yu Hung, Fatma Saaoud, Ying Shao, Yifan Lu, Juanjuan Liu, Bo Yuan, Haiyan Xiang, Hong Wang, Xiaofeng Yang   +9 more
wiley   +1 more source

Fast-switching pH-responsive biomimetic ion channels with bidirectional gating control. [PDF]

Chem Sci
Zhao W, Shi L, Chen J, Ma J, Lv Q, Sun Y, Lv N, Chang X, Xin P.   +8 more
europepmc   +1 more source

Mechanisms and Advanced Characterizations for Urea Electrosynthesis

EcoEnergy, EarlyView.
In this review, various mechanisms and the advanced characterizations involved in urea electrosynthesis are summarized. Furthermore, the outlook on the future potential, the challenges, and scope of these techniques for developing the urea electrosynthesis route are discussed, paving the way for the green synthesis of urea and other important chemicals.
Chu Zhang, Liwei Guo, Shuangli Li, Zihan Chen, Chunshuang Yan, Chade Lv   +5 more
wiley   +1 more source

Multi‐Dimensional Conductive Nanocomposites for Flexible Electronics

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Multi‐dimensional conductive nanocomposites integrate 0D, 1D, and 2D nanomaterials through spatial structure regulation and interface engineering, achieving “1 + 1 > 2” synergistic effects. By leveraging 0D filling to reduce contact resistance, 1D bridging to construct continuous conductive paths, and 2D supporting to enhance mechanical stability ...
Tianyu Wang, Ruimin Cai, Abbas Ali, Lizhe Li, Li Yang, Hulin Zhang, Xuge Fan, Yumin Xia, Wenyong Lai, Linmao Qian, Tiehu Li, Guosheng Shao, Liang Tian   +12 more
wiley   +1 more source

Formulation and Physicochemical Characterization of Capecitabine-Loaded Cubosomes for Enhanced Drug Delivery System. [PDF]

Drug Des Devel Ther
Salawi A.
europepmc   +1 more source

Nonequilibrium Laser Regulation of the Electronic Structure of the Ni‐Based Electrode for Boosting Nucleophilic Electrooxidation of Alcohols

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This work reports an efficient, simple, low‐cost, and scalable method for overall electrode preparation. Nonequilibrium laser synthesis rapidly yields NiO nanocrystals on which a nickel oxyhydroxide (NiOOH) overlayer is grown in situ. By varying the number of laser pulses, the Ni3+/Ni2+ ratio is precisely tuned, thereby modulating the electronic ...
Shilin Fan, Rongxia Zhao, Jianghuai Yuan, Zerui Li, Haotian Yang, Haoyun Sheng, Ran Zhang, Yuxiang Liu, Lin Li, Zhu Liu   +9 more
wiley   +1 more source

Microscopic Exploration of Water Permeation and Ion Rejection for Edge Amine-Functionalized GO Nanoslits. [PDF]

Membranes (Basel)
Pei Y, Li W, Yang X.
europepmc   +1 more source

Hydrogen Permeance and the Effect of H2O and CO on Permeability of Pd0.75Ag0.25 Membranes under Gas-Driven Permeation and Plasma-Driven Permeation

Hydrogen Permeance and the Effect of H2O and CO on Permeability of Pd0.75Ag0.25 Membranes under Gas-Driven Permeation and Plasma-Driven Permeation
identifier:oai:t2r2.star.titech.ac.jp ...
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