Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Ofatumumab, a fully human anti‐CD20 monoclonal antibody, is effective in reducing relapses and disability progression in patients with multiple sclerosis. This study aimed to examine immune profile changes associated with ofatumumab in a prospective cohort of Chinese patients with relapsing–remitting multiple ...
Shu Yang +9 more
wiley +1 more source
A PHOTOMETRIC METHOD FOR THE DETERMINATION OF INULIN IN PLASMA AND URINE
, 1949 Joseph H. Roe +2 more
openalex +1 more source
THE DETERMINATION OF ALBUMIN IN HUMAN BLOOD PLASMA AND SERUM. A METHOD BASED ON THE INTERACTION OF ALBUMIN WITH AN ANIONIC DYE—2-(4′-HYDROXYBENZENEAZO) BENZOIC ACID 12 [PDF]
, 1954 David D. Rutstein +3 more
openalex +1 more source
A 14‐Year Study of Serum Glial Fibrillary Acidic Protein and Total Tau in Premanifest Huntington's
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT There is a pressing need for blood biomarkers that can identify Huntington's disease (HD) gene carriers' proximity to manifest disease. We previously examined serial serum neurofilament light (NfL) concentrations in 21 premanifest HD gene carriers and 14 controls over 14 years, finding that NfL demonstrates high prognostic value and distinct ...
Natalia E. Owen +8 more
wiley +1 more source
Plasma Trough Concentrations of Beta-Lactam Antibiotics in the Early Phase of Septic Shock. [PDF]
Acta Anaesthesiol ScandHägglund M +4 more
europepmc +1 more source
FURTHER STUDIES ON THE LIPOLYTIC SYSTEM INDUCED IN PLASMA BY HEPARIN INJECTION [PDF]
, 1956 D. S. Robinson
openalex +1 more source
CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu +12 more
wiley +1 more source
Quantification of Methylene Blue and Evaluation of Its Pharmacokinetics in ICR Mice by Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry Using Difluoroacetic Acid. [PDF]
Biomed ChromatogrPark SJ +5 more
europepmc +1 more source
Two Types of Diabetes Mellitus, With and Without Available Plasma Insulin [PDF]
, 1951 Joel C. Bornstein, R. D. Lawrence
openalex +1 more source
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden +15 more
wiley +1 more source