Results 31 to 40 of about 2,016,556 (249)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Spatial Distribution Analyses of Axially Long Plasmas under a Multi-Cusp Magnetic Field Using a Kinetic Particle Simulation Code KEIO-MARC

Plasma
To realize the development of a long plasma source with a uniform electron density distribution in the axial direction, the spatial distribution of plasma under a multi-cusp magnetic field was analyzed using a KEIO-MARC code.
Ryota Nishimura, Tomohiro Seino, Keigo Yoshimura, Hiroyuki Takahashi, Akinobu Matsuyama, Kazuo Hoshino, Tetsutarou Oishi, Kenji Tobita   +7 more
doaj   +1 more source

A Plasma-Based Decontamination Process Reveals Potential for an in-Process Surface-Sanitation Method

Plasma, 2022
Methods, which use an indirect plasma treatment for the inactivation of microorganisms in foods, claim a vastly growing field of research. This paper presents a method that uses plasma-processed air (PPA) as a sanitizer.
Thomas Weihe, Uta Schnabel, Mathias Andrasch, Jörg Stachowiak, Frank Tübbecke, Jörg Ehlbeck   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Thermal Plasma Spheroidization and Characterization of Stainless Steel Powders Using Direct Current Plasma Technology

Plasma
The production of spherical powders has recently registered a boost due to the need to fabricate new printing materials for Additive Manufacturing applications, from polymers and resins to metals and ceramics.
Pierpaolo Iovane, Carmela Borriello, Giuseppe Pandolfi, Sabrina Portofino, Gabriella Rametta, Loredana Tammaro, Nicola Fedele, Sergio Galvagno   +7 more
doaj   +1 more source

Simple Parametric Model for Calculation of Lateral Electromagnetic Loads in Tokamaks at Asymmetric Vertical Displacement Events (AVDE)

Plasma, 2022
This paper describes a family of relatively simple numerical models for calculation of asymmetric electromagnetic (EM) loads at all tokamak structures and coils at asymmetric vertical plasma displacement events (AVDE). Unlike currently known AVDE studies
Sergey Sadakov, Fabio Villone, Guglielmo Rubinacci, Salvatore Ventre   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source