Results 171 to 180 of about 1,868,780 (302)

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin, Yongcheng Chen, Yihao Xie, Dongyang Hu, Longhui Gong, Zhihua Chen, Linjie Chen, Minhao Gao, Qizhu Chen, Morgan Jones, Hui Wang, Xiuling You, Kenny Yat Hong Kwan, Shoutao Weng, Taidong Lyu, Xiang Chen, Yuxiao Zhu, Yusheng Wang, Bin Li, Xiangyang Wang, Xiaofeng Jia, Kailiang Zhou, Ouqiang Wu, Aimin Wu   +23 more
wiley   +1 more source

Circulating Bubbles in Decompression Sickness: Pathophysiology and Experimental Models. [PDF]

Biomolecules
Jin Z, Zhu Q, Zheng J, Zhu B, Zhang K, Huang G, Yu X, Xu W.   +7 more
europepmc   +1 more source

Bubbles and Capital Flows [PDF]

This paper presents a stylized model of international trade and asset price bubbles. Its central insight is that bubbles tend to appear and expand in countries where productivity is low relative to the rest of the world.
Jaume Ventura
core  

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

Ultrasound-enhanced hydrogen peroxide generation of microwave plasma discharges in conductive aqueous solutions. [PDF]

Ultrason Sonochem
Honnorat B, Brüser V, Kolb JF.
europepmc   +1 more source

Speculative Price Bubbles in the Rice Market and the 1974 Bangladesh Famine [PDF]

This paper investigates the role played by speculative price bubbles in destabilizing food markets in Bangladesh during the 1974 famine. The hypothesis of speculative price bubbles in the rice market is tested using weekly price data.
Charles Becker, Munir Quddus
core  

Topological Quantum Biomaterials Enable Pyroptosis‐Senescence Coupling for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
This work reports conceptually unprecedented topological quantum biomaterials derived from engineered Pd3Sn nanostrips for oncological applications. Their near‐Fermi‐level electronic architecture and superior interfacial charge transport facilitate ultrasound‐amplified redox reactions and efficient ROS generation.
Zilu Chen, Kun Mei, Yan Yang, Mengna Xu, Xinyue Dai, Renjun Gu, Fuqiong Zhou, Cheng Wang, Meiqi Chang, Yan Huang, Yu Chen   +10 more
wiley   +1 more source

Buried Liquid Metal Interfaces: Oxides and Surface Water-Driven Hydrogen Bubbles. [PDF]

Small
Kim S, Palleau E, Khan MR, Mondal K, So JH, Dickey MD.   +5 more
europepmc   +1 more source

An ATP7A‐Mediated Endogenous Regulation Bio‐Clay Enzyme Enables Self‐Amplified Copper Accumulation for Immunogenic Pyrop

Advanced Science, EarlyView.
A self‐amplifying bio‐clay nanozyme (Bio‐Clayzyme) disrupts tumor metabolic homeostasis through endogenous copper transporter ATPase (ATP7A) downregulation, enhancing cascade catalysis and triggering immunogenic pyroptosis for effective tumor immunotherapy.
Weimin Xie, Yan Li, Guangyao Li, Ying Chen, Huaming Yang   +4 more
wiley   +1 more source

Intravesical gas explosion after sequential greenlight laser prostate vaporization and plasma electrocoagulation: a case report and literature review. [PDF]

Front Urol
Wei J, Zeng Q, Wang Y, Yan G.
europepmc   +1 more source