Results 31 to 40 of about 119,492 (297)
Understanding the spectrum during the tearing mode locking by rotating RMP in J-TEXT
AIP Advances, 2022 The rotating resonant magnetic perturbation (RMP) could lock the tearing mode (TM) and prevent disruption. It is found that the TM instantaneous frequency oscillates during TM locking on the RMP.
Da Li +18 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Nuclear Materials and Energy, 2023 Assessing the performance of the ITER design for the tungsten (W) divertor Plasma Facing Units (PFUs) in a tokamak environment is a high priority issue to ensure efficient plasma operation.
Y. Corre +22 more
doaj +1 more source
Visualization of tokamak operational spaces through the projection of data probability distributions [PDF]
, 2013 Information visualization is becoming an increasingly important tool for making inferences from large and complex data sets describing tokamak operational spaces.
Noterdaeme, Jean-Marie +3 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Adaptive anomaly detection disruption prediction starting from first discharge on tokamak
Nuclear FusionPlasma disruption presents a significant challenge in tokamak fusion, especially in large-size devices like ITER, where it causes severe damage. While current data-driven machine learning methods perform well in disruption prediction, they require ...
X.K. Ai +14 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Nuclear FusionMagnetic islands are believed to be responsible for triggering the internal transport barrier (ITB) around the rational surface and hence improves confinement in magnetic confinement fusion plasma, for more than two decades.
Feiyue Mao +20 more
doaj +1 more source
Observation of plasma confinement in picosecond laser-plasma interactions
Physical Review E, 1993 Novel features associated with multiterawatt laser interactions with solid targets at incident irradiances in the range (1.0--12.0)\ifmmode\times\else\texttimes\fi{}${10}^{17}$ W ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}2}$ are presented. Collimation of the plasma flow normal to the target surface has been observed in time-integrated x-ray images and ion-
Bell, A +13 more
openaire +3 more sources