Results 111 to 120 of about 2,773,444 (301)

Optimization of laser-plasma injector via beam loading effects using ionization-induced injection

, 2017
Simulations of ionization induced injection in a laser driven plasma wakefield show that high-quality electron injectors in the 50-200 MeV range can be achieved in a gas cell with a tailored density profile.
Audet, T. L., Cros, B., Lee, P., Lehe, R., Maynard, G., Vay, J. L.   +5 more
core   +4 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Magnetohydrodynamic Poynting Flux Vortices in the Solar Atmosphere and Their Role in Concentrating Energy

The Astrophysical Journal
The nature of energy generation, transport, and effective dissipation responsible for maintaining a hot solar upper atmosphere is still elusive. The Poynting flux is a vital parameter for describing the direction and magnitude of the energy flow, which ...
Suzana S. A. Silva, Gary Verth, Erico L. Rempel, Istvan Ballai, Shahin Jafarzadeh, Viktor Fedun   +5 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Plasmas and Controlled Fusion [PDF]

Journal of Applied Mechanics, 1962
D. J. Rose, M. Clark, Hans Motz
openaire   +2 more sources

Radiation-resistant Ti/BN coatings: insights from 171 days exposure to space radiation and atomic oxygen in low orbit

npj Materials Degradation
Atmospheric Plasma Spray (APS) and Vacuum Plasma Spray (VPS) techniques were used to develop Ti/2 vol.% hBN coatings, for extreme space environments and tested aboard the International Space Station as part of the MISSE-17 (Materials International Space ...
Abhijith Kunneparambil Sukumaran, Sara Rengifo, William Scott, Annette Gray, Miria Finckenor, Rony Thomas Murickan, Justin McElderry, Matthew Mazurkivich, Michael Renfro, Sang-Hyon Chu, Cheol Park, Anna Wu, Yifei Fu, Sudipta Seal, Arvind Agarwal   +14 more
doaj   +1 more source

EAST plasma equilibrium reconstruction based on weight-adaptive physics-informed neural network

Nuclear Engineering and Technology
This paper introduces a weight-adaptive physics-informed neural network (PINN) for plasma equilibrium reconstruction in the EAST tokamak, overcoming the reliance of conventional approaches on predefined current profile assumptions. The proposed framework
Wenbin Liao, Zhengping Luo, Yao Huang, Yuehang Wang, Zijie Liu, Kai Wu, Dalong Chen, Shengze Cai, Bingjia Xiao   +8 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Working Group 5: Measurements technology and active experiments [PDF]

Technology issues identified by working groups 5 are listed. (1) New instruments are needed to upgrade the ability to measure plasma properties in space. (2) Facilities should be developed for conducting a broad range of plasma experiments in space.
Barfield, J. N., Faelthammar, C.-G., Feynman, J., Quinn, J. N., Roberts, W., Stone, N., Taylor, W. L., Whipple, E.   +7 more
core   +1 more source