Results 91 to 100 of about 2,773,444 (301)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Low-Current High-Voltage Pulsed Atmospheric Arc Plasma Jet: Nanoparticle Emission from the Cathodic Spot

Plasma
The atmospheric pressure plasma jet (APPJ) is a popular type of cold atmospheric plasma (CAP). APPJs based on a pulsed atmospheric arc (PAA) are widely spread in industrial processing.
Dariusz Korzec, Florian Freund, Isabelle Doelfs, Florian Zacherl, Lucas Kudala, Hans-Peter Rabl   +5 more
doaj   +1 more source

Plasma calcining of pigment particles for thermal control coatings [PDF]

, 1972
Method utilizes an RF excited plasma to surface deactivate thermally stable powders at high temperatures. Utilization of this plasma heat treatment at high temperatures can be carried out without grain growth, calcination, or ...
Farley, E. P.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Development of the Langmuir probe under q-distribution for NCST

AIP Advances
The Langmuir probe is one of the important diagnostic methods for measuring the edge plasma parameters of tokamak. A quadruple Langmuir probe (QLP) system was designed and built on the NanChang Spherical tokamak (NCST).
Donghua Xiao, Xiaochang Chen, Sanqiu Liu, Hui Chen, Yuzhen Xiong   +4 more
doaj   +1 more source

Effect of oxygen plasma on nanomechanical silicon nitride resonators

, 2017
Precise control of tensile stress and intrinsic damping is crucial for the optimal design of nanomechanical systems for sensor applications and quantum optomechanics in particular.
Foelske-Schmitz, Annette, Jachimowicz, Artur, Luhmann, Niklas, Sadeghi, Pedram, Sauer, Markus, Schalko, Johannes, Schmid, Silvan   +6 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Application Research on Contour Feature Extraction of Solidified Region Image in Laser Powder Bed Fusion Based on SA-TransUNet

Applied Sciences
The solidified state after the melting of the forming layer in the laser powder bed fusion (LPBF) directly reflects the final forming quality. Compared with the powder layer and the melt pool, it is easier to recognize and remove the defects of contour ...
Mengxiang Dang, Xin Zhou, Guorong Huang, Xuede Wang, Ting Zhang, Ying Tian, Guoquan Ding, Hanyu Gao   +7 more
doaj   +1 more source

The control of the plasma choline concentration in the cat

The Journal of Physiology, 1972
1. Changes in choline concentration of the blood after injections or infusions of choline were studied in cats anaesthetized with chloralose.2. Single I.V. injections of choline 10–100 μmole/kg produced arterial plasma levels 1 min later corresponding to an apparent volume of initial distribution of 430 ml./kg. The concentration then declined rapidly (
J E, Gardiner, W D, Paton
openaire   +3 more sources