Results 91 to 100 of about 1,564,578 (297)

The Impact of Plasma Density Gradients on Lower Band Chorus Wave Propagation

open access: yesGeophysical Research Letters
Plasma density gradients, such as those that occur on plasmaspheric plume boundaries, have been shown to increase the obliquity of lower band chorus.
D. P. Hartley   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Lipoprotein metabolism in hepatic lipase deficiency: studies on the turnover of apolipoprotein B and on the effect of hepatic lipase on high density lipoprotein.

open access: yesJournal of Lipid Research, 1988
Hepatic lipase deficiency produces significant distortion in the plasma lipoprotein profile. Particles with reduced electrophoretic mobility appear in very low density lipoprotein (VLDL).
T Demant   +6 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

The connection of the Ions and electrons in the Earth’s central plasma sheet to the solar wind

open access: yesFrontiers in Astronomy and Space Sciences
The simple problems of the solar wind number density driving the plasma sheet number density and the solar wind speed driving the plasma sheet temperature are examined.
Jose M. Espinoza, Joseph E. Borovsky
doaj   +1 more source

Statistical properties of the plasma fluctuations and turbulent cross-field fluxes in the outboard mid-plane scrape-off layer of Alcator C-Mod

open access: yesNuclear Materials and Energy, 2019
The Alcator C-Mod mirror Langmuir probe diagnostic is used to characterize plasma fluctuations in the outboard mid-plane scrape-off layer (SOL). Ohmically heated L-mode plasmas with Greenwald fractions from 0.1 to 0.45 are analyzed. In plasmas with a low
R. Kube   +6 more
doaj   +1 more source

Generation of powerful terahertz emission in a beam-driven strong plasma turbulence

open access: yes, 2012
Generation of terahertz electromagnetic radiation due to coalescence of upper-hybrid waves in the long-wavelength region of strong plasma turbulence driven by a high-current relativistic electron beam in a magnetized plasma is investigated.
A V Arzhannikov   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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