Results 141 to 150 of about 197,685 (257)

HCV RNA quantification using the Cobas Plasma Separation Card as an alternative to EDTA plasma: a prospective multicenter study. [PDF]

Sci Rep
López AF, Segura AR, Carracedo R, Kessler A, de Salazar González A, Gebreab SZ, Molina E, Parajó N, Pereira S, Vico JR, Escolano ER, Vila M, González LV, Durán AC, Aguilera A, García F, Buti M.   +16 more
europepmc   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Advanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe   +3 more
wiley   +1 more source

Diagnostic accuracy of plasma cell-free DNA qPCR for Schistosoma haematobium assessed by Bayesian latent class analysis in a cohort of pregnant women from Lambaréné, Gabon. [PDF]

Infect Dis Poverty
Hamway Y, Josten T, Abdellatif S, Mukherjee P, Schluckebier J, Berry SPD, Honkpèhedji YJ, Maloum MN, Laclong Lontchi R, Moure PAN, Meulah B, Hoekstra PT, Kroidl I, van Dam GJ, Kreidenweiss A, Esen M, Adégnika AA, Prazeres da Costa C.   +17 more
europepmc   +1 more source

Metal–Organic Framework‐Preserved Thermostable Microneedle Patch for Minimally Invasive Detection and Monitoring of Kidney Dysfunction

Advanced Materials, EarlyView.
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang, Ying Liu, Avishek Debnath, Chuang Li, Zheyu Wang, Gayathri Kondepati, Saketh Balmoori, Jeremiah J. Morrissey, Ying Maggie Chen, Limei Tian, Srikanth Singamaneni   +10 more
wiley   +1 more source

Programmable Functional Silicification of DNA Origami Nanostructures

Advanced Materials, EarlyView.
This work introduces additional functionality into silica‐coated DNA origami nanostructures using non‐standard silica precursors. A fluorescent precursor enables enhanced intracellular tracking, while a disulfide‐containing reagent yields redox‐responsive, degradable silica coatings.
Anna V. Baptist, Lasse Guericke, Philipp Mauker, Oliver Thorn‐Seshold, Amelie Heuer‐Jungemann   +4 more
wiley   +1 more source

Testicular Plasmacytoma as the First Manifestation of Systemic Multiple Myeloma. [PDF]

Diagnostics (Basel)
Rodriguez-Parras P, Zambudio-Munuera A, Herraez-Marcos M, Gutierrez-Tejero F, Arrabal-Polo MA.   +4 more
europepmc   +1 more source

Large‐Scale and Cost‐Effective Fabrication of Ultra‐Thin, Biodegradable Microelectrode Arrays and Pressure Sensors Using Laser Micromachining

Advanced Materials Technologies, EarlyView.
A mask‐free and cost‐effective UV‐pico‐second laser‐based microfabrication method is proposed to fabricate large‐area biodegradable microelectrode arrays and pressure sensors. These devices demonstrate low impedance, good conformability, excellent biocompatibility, and rapid degradation, providing a new route for next‐generation transient electronics ...
Bhavani Prasad Yalagala, Asfand Tanwear, María Cerezo‐Sánchez, Hossein Parvizi, Morteza Amjadi, Hadi Heidari   +5 more
wiley   +1 more source

Evaluation of CSF and plasma tau species as fluid surrogate candidates for tau PET in prodromal to moderate Alzheimer's disease. [PDF]

Alzheimers Dement
Lee J, Olafson E, Toth B, Casavant E, Schauer S, Bittner T, Meyer MR, Verghese PB, Venkatesh V, West T, Braunstein JB, Biever A, Calderon E, Mandl M, Bayfield A, Hoogenraad CC, Teng E, Monteiro C, Anania VG, Bohórquez SMS, Yeh FL.   +20 more
europepmc   +1 more source

At Home Detection of Ovarian Health Biomarker in Menstruation Blood

Advanced Materials Technologies, EarlyView.
A lateral flow assay enables the detection of anti‐Müllerian hormone directly in unprocessed menstrual blood using silica‐gold nanoshells and smartphone‐assisted machine learning analysis. The platform supports decentralized, user‐operated testing in wearable and dipstick formats, highlighting the potential of menstrual blood as a non‐invasive matrix ...
Lucas Dosnon, Thomas Rduch, Salma Sherif Azer, Inge K. Herrmann   +3 more
wiley   +1 more source

Evaluation of Droplet Digital PCR Assay for the Detection of Microsatellite Instability in Colorectal, Gastric, and Endometrial Cancers. [PDF]

Diagnostics (Basel)
Chung Y, Oh S, Nam SK, Kim H, Lee C, Kang GH, Oh HJ, Lee HS, Park KU.   +8 more
europepmc   +1 more source