Results 61 to 70 of about 276,184 (308)

Plasma exchange induces vitamin D deficiency [PDF]

, 2014
BACKGROUND: Plasma exchange is used in the treatment of diseases mediated by pathogenic circulating proteins, or for transplant desensitization. Its non-targeted nature results in the depletion of physiologically important molecules, and it is often ...
Jayne, D R, Schoenmakers, I, Casian, A, Boraks, P, Hiemstra, T F   +4 more
core   +1 more source

Nurses' Performance Regarding Patients Undergoing Therapeutic Plasma Exchange [PDF]

Egyptian Journal of Health Care
Background: Therapeutic plasma exchange is a procedure which removes plasma that contains circulating pathogenic substances, such as auto reactive antibodies, immune complexes, paraproteins, lipoproteins, inflammatory mediators like cytokines and return ...
Hanan Shehata Mohamed, Shimaa Nabil Abd Elsalam Ahmed, Hala Adel Awaad Elsayed, Iman Abdallah Mohammed Abdulmutalib   +3 more
doaj   +1 more source

Plasma Exchange in Alzheimer's Disease

Transfusion Medicine Reviews, 2023
Therapeutic plasma exchange (TPE) has traditionally been used to selectively remove pathologic contents including autoantibodies, abnormal proteins, immune complexes, or toxins from a patient's plasma. In addition to the removal of molecular contributors to disease, fluid replacement and infusion of beneficial plasma constituents including albumin can ...
Lucas Rohrer, Muharrem Yunce, Thomas J. Montine, Hua Shan   +3 more
openaire   +2 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Membrane-based therapeutic plasma exchange in dogs: Prescription, anticoagulation, and metabolic response. [PDF]

, 2019
BACKGROUND Therapeutic plasma exchange (TPE) is used increasingly in small animals to remove circulating large molecular products such as antibodies, pathogenic proteins, and protein-bound toxins.
Francey, Thierry, Ariane Schweighauser, Thierry Francey, Schweighauser, Ariane   +3 more
core   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

A Case Report on the Successful Management of Catastrophic Antiphospholipid Syndrome: Multidisciplinary Approach

Global Journal of Transfusion Medicine
Catastrophic antiphospholipid syndrome (CAPS) is a multi-organ systemic thrombotic condition precipitated due to various secondary conditions such as infection, surgery, and estrogen use.
Pragya Silwal, Aseem Kumar Tiwari, Geet Aggarwal, Chitra Mehta, Yatin Mehta   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Therapeutic plasma exchange in neuro-immunological disorder [PDF]

, 2017
Background: Therapeutic plasma exchange (TPE) is an extracorporeal blood purification technique used to remove high molecular weight substances from the plasma.
Dhivya K., Dhivya x, Latha B., Dhivya x Dhivya K., Aswin Kumar S., B., Latha, S., Aswin Kumar   +5 more
core   +2 more sources

Severe Uncompensated Metabolic Alkalosis due to Plasma Exchange in a Patient with Pulmonary-Renal Syndrome: A Clinician’s Challenge

Case Reports in Critical Care, 2015
Metabolic alkalosis secondary to citrate toxicity from plasma exchange is very uncommon in patients with normal renal function. In patients with advanced renal disease this can be a fatal event.
Mohsin Ijaz, Naeem Abbas, Dmitry Lvovsky
doaj   +1 more source