Results 91 to 100 of about 480,731 (312)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Desenvolvimento de reator de plasma AC aplicado à conversão de hidrocarbonetos [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2014.A degradação do meio ambiente está ligada à ação direta do homem através de atividades ...
Cassini, Felipe Antonio
core  

Ion Acceleration Parameter of the Plasma Focus Device

, 2021
High-energy ion beam emission above megaelectronvolts from the plasma focus strongly correlated with the transient impedance developed across the plasma column.
Yap, Seong Ling, Yap, Seong Shan, Roshan, Mahmud Vahdat   +2 more
core   +1 more source

Retraction: Enhancing radiosensitivity of melanoma cells through very high dose rate pulses released by a plasma focus device. [PDF]

PLoS One, 2023
PLOS ONE Editors.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Parametric profiles of plasma current sheath in argon plasma focus during axial phase

Discover Applied Sciences
This study presents the findings of theoretical and experimental studies into the dynamical behaviors of the plasma current sheath (PCS) and its parameters during the axial phase of plasma focus at the inter-electrode discharge of a 2.2 kJ (EAEA-PF1 ...
Kamal M. Ahmed, H. A. El-sayed, T. M. Allam, A. A. Lashin, H. M. Soliman   +4 more
doaj   +1 more source

Bayesian inference of spectrometric data and validation with numerical simulations of plasma sheath diagnostics of a plasma focus discharge. [PDF]

Sci Rep, 2022
Avaria G, Clausse A, Davis S, Pavez C, Villalba N, Cuadrado O, Moreno J, Ruiz HM, Soto L.   +8 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Leachate treatment using atmospheric plasma [PDF]

openThe treatment of MSW landfill leachate remains a pressing global environmental challenge, largely due to its complex and variable composition that includes high concentrations of organic matter, ammonia, heavy metals, and emerging contaminants ...
KHOKHER, MUHAMMAD OWAIS
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source