Results 41 to 50 of about 14,514,915 (287)

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Control of elongated plasmas in superconductive tokamaks in the absence of in-vessel coils

Nuclear Fusion
The roadmap for the commissioning and first operations of superconductive tokamaks envisages the possibility of running discharges with fairly elongated plasmas before the complete installation of the in-vessel components, including vertical ...
G. De Tommasi, L.E. di Grazia, S. Dubbioso, F. Fiorenza, D. Frattolillo, S. Inoue, M. Mattei, A. Pironti, H. Urano   +8 more
doaj   +1 more source

Drift kinetic theory of the NTM magnetic islands in a finite beta general geometry tokamak plasma

Nuclear Fusion, 2022
In (Imada et al 2019 Nucl. Fusion 59 046016 and references therein) a new 4D drift kinetic nonlinear theory, valid in the limit of a low beta, small inverse aspect ratio, circular cross section, toroidal geometry, to describe the plasma response to the ...
A.V. Dudkovskaia, L. Bardoczi, J.W. Connor, D. Dickinson, P. Hill, K. Imada, S. Leigh, N. Richner, T. Shi, H.R. Wilson   +9 more
doaj   +1 more source

Photospheric magnetic vortex structures [PDF]

, 2011
Using direct numerical magneto-hydrodynamic (MHD) simulations, we demonstrate the evidence of two physically different types of vortex motions in the solar photosphere.
Shelyag, S., Keenan, Francis, F. P. Keenan, Fedun, V., Mathioudakis, Mihalis, Mathioudakis, M., M. Mathioudakis, Shelyag, Sergiy, Erdélyi, Robert, Keenan, F. P., Erdelyi, R., R. Erdélyi, S. Shelyag, V. Fedun, Fedun, Viktor   +14 more
core   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Non-Axisymmetric Tokamak Plasma Equilibrium by 3-D Multi-Layers Method

Applied Sciences
A three-dimensional (3-D) Multi-Layers Method (MLM) of an extension of the axisymmetric version has been developed to compute non-axisymmetric tokamak plasma equilibria with a separatrix.
Jingting Wang, Hiroaki Tsutsui
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Using LQR controller for vertical position control on EAST

Nuclear Fusion
Vertical position control is essential for stabilizing plasma with elongated configurations. The EAST tokamak is equipped with a set of in-vessel control (IC) coils dedicated to this purpose.
Wangyi Rui, Yuehang Wang, Huihui Song, Zhengping Luo, Yao Huang, Qingze Yu, Zijie Liu, Kai Wu, Bingjia Xiao   +8 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source