Results 61 to 70 of about 14,514,915 (287)

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Real-time plasma equilibrium reconstruction and shape control for the MAST Upgrade tokamak

Nuclear Fusion
Real-time magnetic control has been developed to deliver precise control of multiple plasma shape parameters for advanced divertor configurations, including double-null, Super-X, X-point target and X-divertor for the first time on the MAST Upgrade (MAST ...
H. Anand, W. Wehner, D. Eldon, A. Welander, Z. Xing, A. Lvovskiy, J. Barr, E. Cho, B. Sammuli, D. Humphreys, N. Eidietis, A. Leonard, M. Kochan, C. Vincent, G. McArdle, G. Cunningham, A. Thornton, J. Harrison, V. Soukhanovskii, J. Lovell   +19 more
doaj   +1 more source

Extreme ultraviolet imaging of three-dimensional magnetic reconnection in a solar eruption [PDF]

, 2015
X.C., J.Q.S., M.D.D., Y.G., P.F.C. and C.F. are supported by NSFC through grants 11303016, 11373023, 11203014 and 11025314, and by NKBRSF through grants 2011CB811402 and 2014CB744203. C.E.P. and S.J.E. are supported by the UK STFC. J.Z.
Sun, J.Q., Fang, C., Priest, E.R., Guo, Y., Edwards, S.J., Cheng, X., Parnell, C.E., Zhang, J., Ding, M.D., Chen, P.F., Priest, E.R.; id_orcid, Parnell, C.E.; id_orcid   +11 more
core   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Bursty magnetic reconnection at Saturn's magnetopause [PDF]

, 2013
We infer the evolution of magnetopause reconnection from simultaneous in situ magnetopause crossings and auroral observations by Cassini on 19 July 2008.
Masters, Adam, Sergis, Nicholas, Hasegawa, Hiroshi, Fujimoto, Masaki, Grodent, Denis, Radioti, Aikaterini, Coates, A. J., Dougherty, Michele, Badman, Sarah V.   +8 more
core   +4 more sources

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Demonstration of reconstruction-free static magnetic control of DIII-D plasma with deep reinforcement learning

Nuclear Fusion
This paper presents the development and experimental validation of a reinforcement learning (RL)-based magnetic controller on the DIII-D tokamak. The controller directly maps raw magnetic diagnostic signals to actuator commands, replacing the traditional
G.F. Subbotin, D.I. Sorokin, M.R. Nurgaliev, A.A. Granovskiy, I.P. Kharitonov, E.V. Adishchev, E.N. Khairutdinov, R. Clark, H. Shen, W. Choi, J. Barr, D.M. Orlov   +11 more
doaj   +1 more source

Evaluation of Dried Plasma Spot‐Based Quantification of Glial Fibrillary Acidic Protein as a Disease‐Associated Biomarker in Neuromyelitis Optica Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of glial fibrillary acidic protein (GFAP) measured in dried plasma spots versus conventional plasma‐ and serum‐GFAP testing for assessment of disease severity in aquaporin‐4 immunoglobulin G–positive neuromyelitis optica spectrum disorder (AQP4‐IgG+ NMOSD).
Felix Wohlrab, Evelyn Alvarez, Roua Hamdi, Bingqing Zhang, Hayeun Ji, Niyati Jhaveri, Patrick Schindler, Pedro Sanchez, Pia S. Sperber, Tanja Schmitz‐Hübsch, Frederike C. Oertel, Nisa Vorasoot, Najib Kissani, Falko Böhringer, Jens Kuhle, Anne‐Katrin Pröbstel, Xiao‐Jun Ma, Péter Körtvelyessy, Patrick Waters, Friedemann Paul   +19 more
wiley   +1 more source

Periodical plasma structures controlled by external magnetic field

Plasma Sources Science and Technology, 2017
Abstract The characteristics of two-dimensional periodical structures in a magnetized plasma are studied using kinetic simulations. Ridges (i.e. spikes in electron and ion density) are formed and became more pronounced with an increase of magnetic field incidence angle in the plasma volume in the cylindrical chamber.
Schweigert I., Keidar M.
openaire   +2 more sources