Results 121 to 130 of about 1,371,564 (350)

Novel GFP-fused protein probes for detecting phosphatidylinositol-4-phosphate in the plasma membrane

Animal Cells and Systems, 2019
Phosphatidylinositol-4-phosphate (PI4P) plays a crucial role in cellular functions, including protein trafficking, and is mainly located in the cytoplasmic surface of intracellular membranes, which include the trans-Golgi network (TGN) and the plasma ...
Yong-Woo Jun, Jin-A Lee, Deok-Jin Jang
doaj   +1 more source

Brief Report: Dolutegravir Plasma Protein Binding and Unbound Concentrations During Pregnancy and Postpartum. [PDF]

J Acquir Immune Defic Syndr, 2023
Momper JD, Nikanjam M, Best BM, Mirochnick M, Capparelli EV, Cressey TR.   +5 more
europepmc   +1 more source

Identification of GTP‐Binding Proteins by ADP‐Ribosylation in the Presence of Cholera Toxin, Pertussis Toxin and Botulinum Toxin D in Plasma Membrane Isolated from Eggs and Embryos of Sea Urchin [PDF]

, 1992
Yasuyuki Kamata, Shigehisa Furuya, Kaori Takei‐Mikami, Akiko Fujiwara, Ikuo Yasumasu   +4 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Comparison of Two Methods Forecasting Binding Rate of Plasma Protein [PDF]

, 2014
Hongjiu Liu, Yanrong Hu
openalex   +1 more source

Plasma from recovered COVID19 subjects inhibits spike protein binding to ACE2 in a microsphere-based inhibition assay [PDF]

, 2020
Edward P. Gniffke, Whitney E. Harrington, Nicholas Dambrauskas, Yonghou Jiang, Olesya Trakhimets, Vladimir Vigdorovich, Lisa M. Frenkel, D. Noah Sather, Stephen Smith   +8 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Interaction with Blood Proteins of a Ruthenium(II) Nitrofuryl Semicarbazone Complex: Effect on the Antitumoral Activity

Molecules, 2019
The steady rise in the cancer burden and grim statistics set a vital need for new therapeutic solutions. Given their high efficiency, metallodrugs are quite appealing in cancer chemotherapy.
Bruno Demoro, Andreia Bento-Oliveira, Fernanda Marques, João Costa Pessoa, Lucía Otero, Dinorah Gambino, Rodrigo F. M. de Almeida, Ana Isabel Tomaz   +7 more
doaj   +1 more source

Determination of plasma protein binding of dalbavancin. [PDF]

J Antimicrob Chemother, 2022
Turner NA, Xu A, Zaharoff S, Holland TL, Lodise TP.   +4 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source