Fibrinogen and Fibronectin Binding Activity and Immunogenic Nature of Choline Binding Protein M
Background: Choline-binding proteins (CBPs) are a group of surface-exposed proteins, which play crucial and physiological roles in Streptococcus pneumoniae.
Davoud AFSHAR+5 more
doaj
Plasma protein binding prediction focusing on residue-level features and circularity of cyclic peptides by deep learning. [PDF]
Li J+4 more
europepmc +1 more source
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
Neglecting Plasma Protein Binding in COVID-19 Patients Leads to a Wrong Interpretation of Lopinavir Overexposure. [PDF]
Stanke-Labesque F+13 more
europepmc +1 more source
Regulating Protein Immobilization During Cell‐Free Protein Synthesis in Hyaluronan Microgels
Bifunctional microgels carrying a linear DNA template and Ni2+‐activated NTA moieties are used as platform for cell‐free protein synthesis and in situ protein immobilization. By varying the concentration of NTA moieties in the microgels, the amount of GFP‐His immobilized inside the microgel and released to the microgel environment can be regulated ...
Anika Kaufmann+2 more
wiley +1 more source
Characterization of Afb, a novel bifunctional protein in Streptococcus agalactiae
Background and Objectives: Streptococcus agalactiae is the leading cause of bacterial sepsis and meningitis in newborns and results in pneumonia and bacteremia in adults. A number of S.
Sanaz Dehbashi+2 more
doaj
Evaluation of Quantitative Structure Property Relationship Algorithms for Predicting Plasma Protein Binding in Humans. [PDF]
Yun YE+4 more
europepmc +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang+5 more
wiley +1 more source
In silico Plasma Protein Binding Studies of Selected Group of Drugs Using TLC and HPLC Retention Data. [PDF]
Wanat K+3 more
europepmc +1 more source
Integrating selective RNA shortcut, targeted gene isolation, and micro‐arrayed nanoimaging, the NanoPick‐array platform excels in detecting severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) at just 60 copies µL−1 and accurately differentiating variants at the single‐nucleotide level. It ensures 100% accuracy for samples with cycle threshold (
Zixun Wang+9 more
wiley +1 more source