Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Effects of dietary deficiencies of protein and retinol on the plasma level of retinol-binding protein in the rat [PDF]
H. Muhilal, J. Glover
openalex +1 more source
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
wiley +1 more source
Evaluation of Quantitative Structure Property Relationship Algorithms for Predicting Plasma Protein Binding in Humans. [PDF]
Yun YE +4 more
europepmc +1 more source
Human blood plasma proteins modeling and binding affinities with Δ 9 -tetrahydrocannabinol active metabolites: In silico approach [PDF]
Shravan B. Rathod +7 more
openalex +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
In silico Plasma Protein Binding Studies of Selected Group of Drugs Using TLC and HPLC Retention Data. [PDF]
Wanat K +3 more
europepmc +1 more source
Review for "Ebola virus protein VP40 binding to Sec24c for transport to the plasma membrane"
openalex +1 more source
Light‐Controlled Reversible Coassembly of Hybrid Functional Nanostructures
Light‐responsive hybrid nanostructures are formed by coassembling azobenzene‐ and PAH‐functionalized nanoparticles through reversible an tunable π interactions. The system enables tunable coupling between distinct components such as gold and magnetite or carbon nanotubes, producing switchable optical and magnetic properties under light and magnetic ...
Michal Sawczyk +5 more
wiley +1 more source

