Results 11 to 20 of about 1,371,564 (350)
Characterization of plasma protein binding dissociation with online SPE-HPLC. [PDF]
Sci Rep, 2015 Li P, Fan Y, Wang Y, Lu Y, Yin Z.
europepmc +3 more sources
QSAR Development for Plasma Protein Binding: Influence of the Ionization State. [PDF]
Pharm Res, 2018 Toma C +6 more
europepmc +3 more sources
Developmental changes in the extent of drug binding to rat plasma proteins
Scientific Reports, 2023 Binding of therapeutics to proteins in blood plasma is important in influencing their distribution as it is their free (unbound) form that is able to cross cellular membranes to enter tissues and exert their actions.
Fiona Qiu +5 more
doaj +1 more source
An Overview of the Protein Binding of Cephalosporins in Human Body Fluids: A Systematic Review
Frontiers in Pharmacology, 2022 Introduction: Protein binding can diminish the pharmacological effect of beta-lactam antibiotics. Only the free fraction has an antibacterial effect. The aim of this systematic literature review was to give an overview of the current knowledge of protein
C. Jongmans +8 more
doaj +1 more source
Estimation of angiotensin-converting enzyme inhibitors protein binding degree using chromatographic hydrophobicity data [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2015 Introduction. Angiotensin-converting enzyme (ACE) inhibitors represent a significant group of drugs primarily used in the treatment of hypertension and congestive heart failure. Objective.
Trbojević-Stanković Jasna +2 more
doaj +1 more source
Binding and sequestration of poison frog alkaloids by a plasma globulin
eLife, 2023 Alkaloids are important bioactive molecules throughout the natural world, and in many animals they serve as a source of chemical defense against predation.
Aurora Alvarez-Buylla +9 more
doaj +1 more source
Heparin-binding protein as a novel biomarker for sepsis-related acute kidney injury [PDF]
PeerJ, 2020 Background Sepsis-related acute kidney injury (AKI) is associated with high morbidity and mortality among patients. Underlying pathomechanisms include capillary leakage and fluid loss into the interstitial tissue and constant exposure to pathogens ...
Sahra Pajenda +6 more
doaj +2 more sources
Animals, 2022 Sperm-neutrophil binding is an important facet of breeding and significantly impacts fertility. While a specific seminal plasma protein has been found to reduce this binding and improve fertility (CRISP-3), additional molecule(s) appear to promote ...
Abdorrahman S. Alghamdi +7 more
doaj +1 more source
Measles virus glycoprotein-based lentiviral targeting vectors that avoid neutralizing antibodies [PDF]
, 2012 Lentiviral vectors (LVs) are potent gene transfer vehicles frequently applied in research and recently also in clinical trials. Retargeting LV entry to cell types of interest is a key issue to improve gene transfer safety and efficacy.
Abel, Tobias +5 more
core +6 more sources
Nanomaterials, 2023 Carboranes are promising agents for applications in boron neutron capture therapy (BNCT), but their hydrophobicity prevents their use in physiological environments.
Tainah Dorina Marforio +3 more
doaj +1 more source