High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires+4 more
wiley +1 more source
Pharmacokinetics, metabolism, and excretion of [<sup>14</sup>C]-valemetostat in healthy male participants, and in vitro plasma protein binding. [PDF]
Tachibana M+7 more
europepmc +1 more source
The Use of Pseudo-Equilibrium Constant Affords Improved QSAR Models of Human Plasma Protein Binding
Xiang-Wei Zhu+4 more
semanticscholar +1 more source
A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou+5 more
wiley +1 more source
Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG. [PDF]
Bellier JP+15 more
europepmc +1 more source
The Impact of Plasma Protein Binding Characteristics and Unbound Concentration of Voriconazole on Its Adverse Drug Reactions. [PDF]
Yuan ZQ+9 more
europepmc +1 more source
High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein. [PDF]
Björn Dahlbäck, Johan Stenflo
openalex +1 more source
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee+12 more
wiley +1 more source