Results 221 to 230 of about 2,396,679 (391)

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

The Enhancement of Fluorescence and the Decreased Susceptibility to Enzymatic Oxidation of Retinol Complexed with Bovine Serum Albumin, β-Lactoglobulin, and the Retinol-binding Protein of Human Plasma

, 1972
Sidney Futterman, J Heller
openalex   +1 more source

Implications of Plasma Protein Binding for Pharmacokinetics and Pharmacodynamics of the γ-Secretase Inhibitor RO4929097

Clinical Cancer Research, 2012
Jianmei Wu, P. LoRusso, L. Matherly, Jing Li   +3 more
semanticscholar   +1 more source

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

Advanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han, Godfrey Mwiti, Seo‐Joon Yeom, Jaeyoon Lim, Woo Sik Kim, Sangyong Lim, Seung‐Taik Lim, Eui‐Baek Byun   +7 more
wiley   +1 more source

A method for estimation of plasma protein binding using diffusion ordered NMR spectroscopy (DOSY). [PDF]

RSC Med Chem
Taylor R, Swift T, Wilkinson D, Afarinkia K.   +3 more
europepmc   +1 more source

A rapid and sensitive bioanalytical LC-MS/MS method for the quantitation of a novel CDK5 inhibitor 20-223 (CP668863) in plasma: Application to in vitro metabolism and plasma protein-binding studies. [PDF]

Biomed Chromatogr, 2020
Bala V, Chhonker YS, Sleightholm RL, Crawford AJ, Hollingsworth MA, Murry DJ.   +5 more
europepmc   +1 more source

Relationship of food intake to the induction of plasma sex steroid-binding protein and testicular activity in immature male little brown bats (Myotis lucifugus lucifugus) [PDF]

, 1985
D. A. Damassa, A. W. Gustafson
openalex   +1 more source

Glucose induces lipolytic cleavage of a glycolipidic plasma membrane anchor in yeast [PDF]

, 1993
Bandlow, Wolfhard, Müller, Günter
core   +2 more sources

Cefazolin plasma protein binding and its covariates in neonates

European Journal of Clinical Microbiology and Infectious Diseases, 2012
A. Smits, A. Kulo, A. Kulo, R. Verbesselt, Gunnar Naulaers, J. Hoon, P. Vermeersch, K. Allegaert   +7 more
semanticscholar   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source