Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang+9 more
wiley +1 more source
Estimation of the distance between the divalent cation binding site of des-1-41-light chain-activated bovine plasma protein C and a nitroxide spin label attached to the active-site serine residue [PDF]
K A Hill+2 more
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Two lipid-anchored cAMP-binding proteins in the yeast Saccharomyces cerevisiae are unrelated to the R subunit of cytoplasmic protein kinase A [PDF]
Bandlow, Wolfhard, Müller, Günter
core +1 more source
Canine Albumin Polymorphisms and Their Impact on Drug Plasma Protein Binding. [PDF]
Costa AP+5 more
europepmc +1 more source
SecA protein, a peripheral protein of the Escherichia coli plasma membrane, is essential for the functional binding and translocation of proOmpA. [PDF]
Kyle W. Cunningham+6 more
openalex +1 more source
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan+13 more
wiley +1 more source
The early changes in retinol-binding protein and prealbumin concentrations in plasma of protein–energy malnourished children after treatment with retinol and an improved diet [PDF]
Suzanne Large+4 more
openalex +1 more source
Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa+5 more
wiley +1 more source
Plasma protein binding of phenytoin in 100 epileptic patients. [PDF]
GM Peterson+4 more
openalex +1 more source