Results 281 to 290 of about 1,371,564 (350)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

The seminal plasma proteome dataset of the giant panda. [PDF]

Data Brief
Zhou S, Wang T, Chen J, Li F, Wang S, Hu X, Zhang M, Hou R, Liu Y, Cai K.   +9 more
europepmc   +1 more source

The BRAF-specific region suppresses cysteine-rich domain-lipid interaction independently of canonical autoinhibition by the 14-3-3 dimer. [PDF]

Protein Sci
Revazishvili V, Morales A, Baxter B, Grim J, Chakhrakia A, Jimenez Salinas A, Tevdorashvili K, Riestra AM, Lee YK.   +8 more
europepmc   +1 more source

Gut plasma membrane proteomes of adults and larvae of the European honey bee, Apis mellifera. [PDF]

Sci Rep
Arora AK, Mishra R, Bonning BC.
europepmc   +1 more source

AI-Powered Identification of Human Cell Surface Protein Interactors of the Hemagglutinin Glycoprotein of High-Pandemic-Risk H5N1 Influenza Virus. [PDF]

Viruses
Poitras C, Coulombe B.
europepmc   +1 more source

Exploring the impact of age, sex and life experiences on plasma inflammatory profiles through comparative proteomics. [PDF]

Front Immunol
Bartolucci M, Utyro O, Muraglia A, Repetto A, Agostini V, Pizzonia M, Ottaviani S, Tripodi G, Filaci G, Cancedda R, Petretto A, Mastrogiacomo M.   +11 more
europepmc   +1 more source

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Lidocaine plasma protein binding

Clinical Pharmacology and Therapeutics, 1980
The percent of unbound lidocaine in the plasma of 24 healthy subjects was measured by equilibrium dialysis after addition of 3 microgram/ml C14 lidocaine hydrochloride. The percentage of unbound lidocaine varied from 19.9 to 38.8 (30.2 +/- 5, mean +/- SD) was inversely related to the concentration of alpha 1-acid glycoprotein (AAG) in the plasma (r ...
P A, Routledge, A, Barchowsky, T D, Bjornsson, B B, Kitchell, D G, Shand   +4 more
openaire   +2 more sources

Progesterone Binding Plasma Protein (PBP)

Nature, 1970
SINCE Seal et al.1 showed that, in the human plasma, the high affinity binding of progesterone is due to the corticosteroid binding globulin (CBG), it has been assumed by most investigators that this is the case in all species and in all conditions.
E, Milgrom, M, Atger, E E, Baulieu
openaire   +2 more sources

Plasma Protein Binding of Bepridil

The Journal of Clinical Pharmacology, 1985
The binding of the calcium‐channel blocking agent, bepridil HCl (Vascor), to plasma proteins was investigated using radiolabeled bepridil and equilibrium dialysis. Greater than 99.7% of added bepridil‐14C was found to freshly collected human plasma. The binding was characterized by a saturable high‐affinity site (KD = 32 ng/mL = 87 nM) on alpha1‐acid ...
J F, Pritchard, L A, McKown, B H, Dvorchik, P J, O'Neill   +3 more
openaire   +2 more sources

Plasma protein binding of ceftriaxone

Xenobiotica, 1987
1. The plasma protein binding characteristics of ceftriaxone, a new cephalosporin antibiotic, were determined in human, baboon, rabbit, dog and rat plasma. 2. The protein binding of ceftriaxone was similar and concentration-dependent in human, baboon, rabbit and rat plasma, being highly bound (90-95%) at low concentrations (less than 100 micrograms/ml)
A C, Popick, W G, Crouthamel, I, Bekersky   +2 more
openaire   +2 more sources