Results 21 to 30 of about 1,339,631 (349)

Measles virus glycoprotein-based lentiviral targeting vectors that avoid neutralizing antibodies [PDF]

, 2012
Lentiviral vectors (LVs) are potent gene transfer vehicles frequently applied in research and recently also in clinical trials. Retargeting LV entry to cell types of interest is a key issue to improve gene transfer safety and efficacy.
Abel, Tobias, Brynza, Julia, Buchholz, Christian J., Kneissl, Sabrina, Rasbach, Anke, Schneider-Schaulies, Jürgen   +5 more
core   +7 more sources

VAMP721 conformations unmask an extended motif for K+ channel binding and gating control [PDF]

, 2016
Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins play a major role in membrane fusion and contribute to cell expansion, signaling, and polar growth in plants.
Blatt, Mike R., Donald, Naomi Alice, Karnik, Rucha, Waghmare, Sakharam, Zhang, Ben   +4 more
core   +2 more sources

High resolution crystal structure data of human plasma retinol-binding protein (RBP4) bound to retinol and fatty acids

Data in Brief, 2018
Retinol is transported in vertebrate plasma bound to a protein called retinol-binding protein (RBP4) so far believed to be specific for the vitamin. When the protein is saturated with retinol it binds tightly to another plasma protein, transthyretin ...
Massimiliano Perduca, Stefania Nicolis, Barbara Mannucci, Monica Galliano, Hugo L. Monaco   +4 more
doaj   +1 more source

Binding Affinity and Capacity for the Uremic Toxin Indoxyl Sulfate

Toxins, 2014
Protein binding prevents uremic toxins from removal by conventional extracorporeal therapies leading to accumulation in maintenance dialysis patients. Weakening of the protein binding may enhance the dialytic elimination of these toxins.
Eric Devine, Detlef H. Krieter, Marieke Rüth, Joachim Jankovski, Horst-Dieter Lemke   +4 more
doaj   +1 more source

Simultaneous determination of human plasma protein binding of bioactive flavonoids in Polygonum orientale by equilibrium dialysis combined with UPLC–MS/MS

Journal of Pharmaceutical Analysis, 2013
A simple and selective ultra performance liquid chromatography–electrospray ionization tandem mass spectrometry (UPLC–ESI-MS/MS) assay was developed for the determination of the human plasma protein binding of four bioactive flavonoids (such as ...
Yong Huang, Hui Chen, Feng He, Zhi-Rong Zhang, Lin Zheng, Yue Liu, Yan-Yu Lan, Shang-Gao Liao, Yong-Jun Li, Yong-Lin Wang   +9 more
doaj   +1 more source

The hepta-β-glucoside elicitor-binding proteins from legumes represent a putative receptor family [PDF]

, 2000
The ability of legumes to recognize and respond to β-glucan elicitors by synthesizing phytoalexins is consistent with the existence of a membrane-bound β-glucan-binding site.
Ebel, J., Fliegmann, J., Mithöfer, A., Neuhaus-Url, G., Schwarz, H.   +4 more
core   +1 more source

Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking [PDF]

, 2018
Extracellular calcium flow through neuronal voltage-gated CaV2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the ...
Chen, Xingjuan, Ghozayel, Mona K., Liu, Degang, Meroueh, Samy O., Obukhov, Alexander G., Ripsch, Matthew S., Si, Yubing, Stamatkin, Christopher W., White, Fletcher A., Xu, David, Zhou, Donghui   +10 more
core   +1 more source

Vitamin A transport in plasma of the non-mammalian vertebrates: isolation and partial characterization of piscine retinol-binding protein1

Journal of Lipid Research, 1977
Studies were conducted to explore vitamin A transport in the non-mammalian vertebrates, especially Pisces, Amphibia, and Reptilia, and to isolate and partially characterize piscine retinol-binding protein.
Y Shidoji, Y Muto
doaj   +1 more source

Interaction of antithrombin III with surface-immobilized albumin-heparin conjugates [PDF]

, 1995
The interaction between antithrombin III (ATIII) and albumin-heparin conjugates covalently coupled onto carboxylated polystyrene beads either in buffer containing albumin or in plasma was studied using 14C-labeled ATIII.
Delden, C.J. van, Engbers, G.H.M., Feijen, Jan   +2 more
core   +3 more sources

Photoaffinity Labeling of Plasma Proteins

Molecules, 2013
Photoaffinity labeling is a powerful technique for identifying a target protein. A high degree of labeling specificity can be achieved with this method in comparison to chemical labeling.
Masaki Otagiri, Victor Tuan Giam Chuang
doaj   +1 more source