Results 41 to 50 of about 1,339,631 (349)
The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]
, 2010 Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L. +4 more
core +2 more sources
Acta Pharmaceutica Sinica B, 2014 DRDE-07, a newly synthesized amifostine analog currently under clinical investigation in a phase I trial, is a potent antidote against sulfur mustard toxicity.
Pankaj Verma, Rajagopalan Vijayaraghavan
doaj +1 more source
Acta Pharmaceutica, 2020 The present study is aimed at computational prediction of the molecular interactions between resveratrol, celecoxib, leflunomide and human serum albumin (HSA) and then investigates the plasma protein binding of resveratrol combined with celecoxib or ...
Zhou Peng, Hua Fang
doaj +1 more source
Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals. [PDF]
, 2015 BackgroundClinically significant dysregulation of the insulin-like growth factor (IGF) family proteins occurs in HIV-infected individuals, but the details including whether the deficiencies in IGFs contribute to CNS dysfunction are unknown.MethodsWe ...
Choi, Namjong +4 more
core +2 more sources
THE BINDING OF MYOGLOBIN BY PLASMA PROTEIN [PDF]
The Journal of Experimental Medicine, 1960 When added to dog plasma in vitro and in vivo, myoglobin was bound to plasma protein in a concentration which, maximally, averaged 21 ± 6 mg. per cent. Electrophoretically, bound myoglobin was separated from free myoglobin and migrated between alpha-2 and beta globulin.
openaire +3 more sources
Allosteric modulation of zinc speciation by fatty acids [PDF]
Background: Serum albumin is the major protein component of blood plasma and is responsible for the circulatory transport of a range of small molecules that include fatty acids, hormones, metal ions and drugs.
Barnett, James P., Dr. +6 more
core +1 more source
Analysis of species-dependent hydrolysis and protein binding of esmolol enantiomers
Journal of Pharmaceutical Analysis, 2012 The stereoselective hydrolysis of esmolol in whole blood and in its separated components from rat, rabbit and human was investigated. Blood esterase activities were variable in different species in the order of rat>rabbit>human.
Yi-Hong Tang +4 more
doaj +1 more source
Design of Beta-2 Microglobulin Adsorbent Protein Nanoparticles
Biomolecules, 2023 Beta-2 microglobulin (B2M) is an immune system protein that is found on the surface of all nucleated human cells. B2M is naturally shed from cell surfaces into the plasma, followed by renal excretion.
Justin E. Miller +8 more
doaj +1 more source
Plasma protein binding of chlorpromazine
Journal of Pharmacy and Pharmacology, 1970 AbstractMore than 90% of the plasma content of chlorpromazine over a concentration range from 0·008 to 15·1 μg/ml was bound to human plasma protein. Binding was affected by the pH of the aqueous medium; with few exceptions the higher values were obtained at the higher pH values.
openaire +3 more sources
Binding of Novobiocin with Plasma Proteins
Experimental Biology and Medicine, 1957 Summary1. Fraction studies with plasma from a dog treated with novobiocin showed that novobiocin is extensively bound to plasma albumin. 2.
Gunther W. Kuron +4 more
openaire +3 more sources