Results 41 to 50 of about 1,371,564 (350)
Acta Pharmaceutica, 2020 The present study is aimed at computational prediction of the molecular interactions between resveratrol, celecoxib, leflunomide and human serum albumin (HSA) and then investigates the plasma protein binding of resveratrol combined with celecoxib or ...
Zhou Peng, Hua Fang
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Blood Plasma Exosomes Contain Circulating DNA in Their Crown
Diagnostics, 2022 It is known that circulating DNA (cirDNA) is protected from nuclease activity by proteins that form macromolecular complexes with DNA. In addition, it was previously shown that cirDNA can bind to the outer surface of exosomes.
Oleg Tutanov +5 more
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Nanoclustering as a dominant feature of plasma membrane organization [PDF]
, 2014 Early studies have revealed that some mammalian plasma membrane proteins exist in small nanoclusters. The advent of super-resolution microscopy has corroborated and extended this picture, and led to the suggestion that many, if not most, membrane ...
Cambi, Alessandra +4 more
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Acta Pharmaceutica Sinica B, 2014 DRDE-07, a newly synthesized amifostine analog currently under clinical investigation in a phase I trial, is a potent antidote against sulfur mustard toxicity.
Pankaj Verma, Rajagopalan Vijayaraghavan
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Increased circulating levels of vitamin D binding protein in MS patients [PDF]
, 2015 Vitamin D (vitD) low status is currently considered a main environmental factor in multiple sclerosis (MS) etiology and pathogenesis. VitD and its metabolites are highly hydrophobic and circulate mostly bound to the vitamin D binding protein (DBP) and ...
Cortese, Antonio +9 more
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Allosteric modulation of zinc speciation by fatty acids [PDF]
Background: Serum albumin is the major protein component of blood plasma and is responsible for the circulatory transport of a range of small molecules that include fatty acids, hormones, metal ions and drugs.
Barnett, James P., Dr. +6 more
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Vitamin A Transport Mechanism of the Multitransmembrane Cell-Surface Receptor STRA6. [PDF]
, 2015 Vitamin A has biological functions as diverse as sensing light for vision, regulating stem cell differentiation, maintaining epithelial integrity, promoting immune competency, regulating learning and memory, and acting as a key developmental morphogen ...
Kassai, Miki +4 more
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Analysis of species-dependent hydrolysis and protein binding of esmolol enantiomers
Journal of Pharmaceutical Analysis, 2012 The stereoselective hydrolysis of esmolol in whole blood and in its separated components from rat, rabbit and human was investigated. Blood esterase activities were variable in different species in the order of rat>rabbit>human.
Yi-Hong Tang +4 more
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Design of Beta-2 Microglobulin Adsorbent Protein Nanoparticles
Biomolecules, 2023 Beta-2 microglobulin (B2M) is an immune system protein that is found on the surface of all nucleated human cells. B2M is naturally shed from cell surfaces into the plasma, followed by renal excretion.
Justin E. Miller +8 more
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The High Plasma Retinol Binding Protein 4 Level as a Risk Factor Consequently of Type 2 Diabetes Mellitus of Abdominal Obesity [PDF]
, 2011 Abdominal obesity (Ab-Ob) related to cardiometabolic risk, that is riskfactor constellation for succeeded cardiovasculer disease and type 2 DiabetesMellitus (DM).
Astawa, N. M. (Nyoman) +3 more
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