Results 51 to 60 of about 1,940,623 (276)
ProNet DB: A proteome-wise database for protein surface property representations and RNA-binding profiles [PDF]
arXiv, 2022 The rapid growth in the number of experimental and predicted protein structures and more complicated protein structures challenge users in computational biology for utilizing the structural information and protein surface property representation. Recently, AlphaFold2 released the comprehensive proteome of various species, and protein surface property ...
arxiv
THE BINDING OF MYOGLOBIN BY PLASMA PROTEIN [PDF]
The Journal of Experimental Medicine, 1960 When added to dog plasma in vitro and in vivo, myoglobin was bound to plasma protein in a concentration which, maximally, averaged 21 ± 6 mg. per cent. Electrophoretically, bound myoglobin was separated from free myoglobin and migrated between alpha-2 and beta globulin.
openaire +3 more sources
Design of Beta-2 Microglobulin Adsorbent Protein Nanoparticles
Biomolecules, 2023 Beta-2 microglobulin (B2M) is an immune system protein that is found on the surface of all nucleated human cells. B2M is naturally shed from cell surfaces into the plasma, followed by renal excretion.
Justin E. Miller +8 more
doaj +1 more source
Controlling the folding and substrate-binding of proteins using polymer brushes [PDF]
Physical Review Letters 108 208104 (2012), 2012 The extent of coupling between the folding of a protein and its binding to a substrate varies from protein to protein. Some proteins have highly structured native states in solution, while others are natively disordered and only fold fully upon binding.
arxiv +1 more source
Binding of Novobiocin with Plasma Proteins
Experimental Biology and Medicine, 1957 Summary1. Fraction studies with plasma from a dog treated with novobiocin showed that novobiocin is extensively bound to plasma albumin. 2.
Gunther W. Kuron +4 more
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Decreased protein binding of moxifloxacin in patients with sepsis?
GMS Infectious Diseases, 2017 The mean (SD) unbound fraction of moxifloxacin in plasma from patients with severe sepsis or septic shock was determined by ultrafiltration to 85.5±3.0% (range 81.9 and 91.6%) indicating a decreased protein binding of moxifloxacin in this population ...
Dorn, Christoph +6 more
doaj +1 more source
Journal of Pharmacy and Science, 2013 Liraglutide is a human glucagon-like peptide-1 (GLP-1) analogue approved for the treatment of type 2 diabetes. It is based on human GLP-1 with the addition of a 16-carbon fatty acid, which facilitates binding to plasma proteins, thus prolonging the ...
A. Plum, L. Jensen, J. B. Kristensen
semanticscholar +1 more source
Toxics, 2023 Concern over per- and polyfluoroalkyl substances (PFAS) has increased as more is learned about their environmental presence, persistence, and bioaccumulative potential.
Anna Kreutz +6 more
doaj +1 more source
Characterization of Binding of Raltegravir to Plasma Proteins [PDF]
Antimicrobial Agents and Chemotherapy, 2013 ABSTRACT The objective of this study was to characterize raltegravir (RAL) binding to albumin and alpha-1-acid glycoprotein (AAG). Unbound and bound RAL were separated by ultrafiltration. The association constant ( K a ) was estimated by a graphical method.
Caroline Barau +6 more
openaire +3 more sources
Toxics, 2023 Few studies are available on the environmental and toxicological effects of perfluoroalkyl ether carboxylic acids (PFECAs), such as GenX, which are replacing legacy PFAS in manufacturing processes.
Aero Renyer +7 more
doaj +1 more source