Results 251 to 260 of about 2,312,825 (297)

Desipramine Plasma Concentration and Antidepressant Response

Archives of General Psychiatry, 1982
The relationship of desipramine hydrochloride plasma concentration and antidepressant response was determined in 30 depressed inpatients treated for three weeks with desipramine. All patients had a nondelusional unipolar depression, met DSM-III criteria for major depressive episode with melancholia, and had a Hamilton score of 18 or greater after one ...
J C, Nelson, P, Jatlow, D M, Quinlan, M B, Bowers   +3 more
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Nortriptyline plasma levels and therapeutic response

Clinical Pharmacology & Therapeutics, 1976
Eighteen depressed outpatients were treatedfor 6 wk with a mean daily dose of 121 mg of nortriptyline. The mean plasma level was 138 ng/ml during treatment. Therapeutic response was monitored by the Zung Self‐Rating Depression Scale and the Hamilton Depression Scale administrered by two psychiatrists blind to the tricyclic used, dose, and plasma levels.
V E, Ziegler, P J, Clayton, J R, Taylor, B, Tee, J T, Biggs   +4 more
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Escitalopram plasma levels and antidepressant response

European Neuropsychopharmacology, 2017
Major Depression Disorder (MDD) has a highly variable treatment response due to the large inter-individual variation in the pharmacokinetics and pharmacodynamics of drug treatments. In detail the correlation between plasma level and efficacy has been much debated. Among first-line drugs for MDD, one of the most used is escitalopram.
Florio, Vincenzo, Porcelli, Stefano, Saria, Alois, Serretti, Alessandro, Conca, Andreas   +4 more
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Doxepin Plasma Levels and Anxiolytic Response

International Pharmacopsychiatry, 1980
A study of 23 patients (16 females, 7 males), diagnosed as suffering from anxiety, was carried out using a flexible dosage regimen of doxepin. Hamilton Anxiety Rating Scale scores were assessed on days 0, 7, 14 and 21 and plasma doxepin and desmethyl-doxepin concentrations were analysed from blood samples taken on days 7, 14 and 21 of the trial.
T R, Norman, G D, Burrows, G N, Bianchi, K P, Maguire, J M, Wurm   +4 more
openaire   +2 more sources

Parathyroid response during therapeutic plasma exchange

Transfusion, 1983
ABSTRACT: Significant hypocalcemia is infrequently encountered during therapeutic plasma exchange. An increase in parathyroid hormone secretion during the procedure may be responsible for maintaining the calcium levels.
M B, Bongiovanni, J E, Strauss, E M, Ziselman, H A, Wurzel   +3 more
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Amitriptyline plasma levels and therapeutic response

Clinical Pharmacology & Therapeutics, 1976
Eighteen depressed outpatients were treatedfor 6 wk with amitriptyline. Clinical improvement was monitored using the Hamilton Depression Rating Scale administered by two psychiatrists blind to the tricyclic used for treatment, dosage, and plasma levels.
V E, Ziegler, B T, Co, J R, Taylor, P J, Clayton, J T, Biggs   +4 more
openaire   +2 more sources

Plasma biopterin levels and tetrahydrobiopterin responsiveness

Molecular Genetics and Metabolism, 2005
Tetrahydrobiopterin (BH4) responsive hyperphenylalaninemia (HPA) with a mutant phenylalanine hydroxylase (PAH) gene was found during neonatal screening for PKU. This study determined blood BH4 and phenylalanine in two patients with hyperphenylalaninemia following oral load with BH4 10 mg/kg. Our patients underwent neonatal screening for PKU, had normal
Haruo, Shintaku, Hiroki, Fujioka, Yoshitomo, Sawada, Minoru, Asada, Tsunekazu, Yamano   +4 more
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Viloxazine plasma concentrations and clinical response

Journal of Affective Disorders, 1980
Eleven patients suffering from primary depressive illness were treated with 300 mg/d of viloxazine for 29 days. Blood samples were collected at weekly intervals and severity of depression assessed using the Hamilton depression rating scale. Mean plasma viloxazine level for all patients during the trial was 1.20 micrograms/ml and ranged from 0.40 to 2 ...
T R, Norman, G D, Burrows, B M, Davies, K P, Maguire, J M, Wurm   +4 more
openaire   +2 more sources

Duloxetine plasma level and antidepressant response

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2019
Major Depressive Disorder (MDD) is associated with a high rate of inadequate treatment response, which is mainly due to the large inter-individual genetic variability in pharmacokinetic and pharmacodynamic targets of antidepressant drugs. Little is still known about the exact association between plasma level of first-line antidepressants and clinical ...
De Donatis, Domenico, Florio, Vincenzo, Porcelli, Stefano, Saria, Alois, Mercolini, Laura, Serretti, Alessandro, Conca, Andreas   +6 more
openaire   +3 more sources

Trifluoperazine Plasma Levels and Clinical Response

Journal of Clinical Psychopharmacology, 1989
The authors studied 36 acutely psychotic inpatients who were diagnosed as having either a schizophrenic (N = 30) or other psychotic (N = 6) disorder. After a washout phase averaging 18 days, all patients were placed on trifluoperazine 5 mg orally twice a day.
P G, Janicak, J I, Javaid, R P, Sharma, J E, Comaty, J, Peterson, J M, Davis   +5 more
openaire   +2 more sources