Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Interval‐induced metabolic perturbation determines tissue fluid shifts into skeletal muscle
Intense interval exercise has proven to be as effective as traditional endurance exercise in improving maximal oxygen uptake. Shared by these two exercise regimes is an acute reduction in plasma volume, which is a suggested stimulus behind exercise ...
Mirko Mandić +6 more
doaj +1 more source
Calculated Plasma Volume Status Is Associated With Mortality in Acute Respiratory Distress Syndrome
OBJECTIVES:. The optimal method to assess fluid overload in acute respiratory distress syndrome is not known, and current techniques have limitations. Plasma volume status has emerged as a noninvasive method to assess volume status and is defined as the ...
Shannon E. Niedermeyer, MD +3 more
doaj +1 more source
Ultra-trace Cu isotope ratio measurements via multi-collector ICP-mass spectrometry using Ga as internal standard : an approach applicable to micro-samples [PDF]
The capabilities of Cu isotope ratio measurements are often restricted by the small volumes of sample available and/or their low Cu concentration. In this work, an analytical approach was developed for performing Cu isotopic analysis via multi-collector ...
Costas Rodriguez, Marta +2 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Measuring The Equations Of State In A Relaxed Magnetohydrodynamic Plasma [PDF]
We report measurements of the equations of state of a fully relaxed magnetohydrodynamic (MHD) laboratory plasma. Parcels of magnetized plasma, called Taylor states, are formed in a coaxial magnetized plasma gun, and are allowed to relax and drift into a ...
Barbano, Luke J., , \u2718 +5 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Leg oedema—A diagnostic approach
Oedema results from excess accumulation of interstitial fluid and produces palpable swelling. Its major causes include venous obstruction, increased capillary permeability, and increased plasma volume secondary to sodium and water retention.
Taposh Sarkar +4 more
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Analysis of one- and two-particle spectra at RHIC based on a hydrodynamical model [PDF]
We calculate the one-particle hadronic spectra and correlation functions of pions based on a hydrodynamical model. Parameters in the model are so chosen that the one-particle spectra reproduce experimental results of $\sqrt{s}=130A$GeV Au+Au collisions ...
C Adler +11 more
core +2 more sources

