Results 161 to 170 of about 1,085,040 (311)

Mutation in ESBL Plasmid from Escherichia coli O104:H4 Leads Autoagglutination and Enhanced Plasmid Dissemination [PDF]

, 2018
Mickaël Poidevin, Mari Sato, Ipek Altinoglu, Manon Delaplace, Chikara Sato, Yoshiharu Yamaichi   +5 more
openalex   +1 more source

Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro

Advanced Biology, EarlyView.
Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Alice Grossi, Paola Fulghieri, Abdurakhmon Aduvaliev, Karen Soffiantini, Irene Oldrati, Margherita Cavallo, Marco Biggiogera, Giorgia Pellavio, Umberto Laforenza, Monica Savio, Virginie Sottile   +10 more
wiley   +1 more source

Transcription factor CEBPA suppresses sepsis induced lung injury by activating SIRT4 transcription. [PDF]

Sci Rep
Wu Z, Gou K, Wang Y, Dai L.
europepmc   +1 more source

Preclinical evaluation of the immunogenicity and safety of plasmid DNA-based prophylactic vaccines for human cytomegalovirus [PDF]

, 2012
Jukka Hartikka, Vesselina Bozoukova, Jane Morrow, Denis Rusalov, Mark Shlapobersky, Qun Wei, Sou Boutsaboualoy, Ming Ye, Mary K. Wloch, John A. Doukas, Seán M. Sullivan, Alain Rolland, Larry Smith   +12 more
openalex   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Circling in on plasmids: benchmarking plasmid detection and reconstruction tools for short-read data from diverse species. [PDF]

Brief Bioinform
Teixeira M, Souque C, Worby CJ, Shea T, Commins N, Smith JT, Miklos AM, Abeel T, Earl AM, Manson AL.   +9 more
europepmc   +1 more source

A Sustainable Biotechnology Approach for Mineral Separation

Advanced Functional Materials, EarlyView.
Silver‑binding peptides are first identified through phage‐display screening, and then engineered into multifunctional and responsive peptides or proteins. These tailored biomolecules can selectively capture and aggregate silver particles or ions from complex mixtures, enabling rapid and efficient silver separation and recovery.
Guangze Yang, Yun Liu, Shankar Raj Devkota, Yue Hui, Ruilin Zhao, Yang Li, David A. Weitz, Chun‐Xia Zhao   +7 more
wiley   +1 more source

A global soil plasmidome resource unveils functional and ecological roles of plasmids in soil microbiomes. [PDF]

Nat Commun
Fiamenghi MB, Camargo AP, Ivanova NN, Graham EB, Wu R, Hofmockel KS, Kyrpides NC.   +6 more
europepmc   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Characterisation of Plasmid-Associated Antimicrobial Resistance Genes in Coastal Marine <i>Enterobacterales</i> from the Central Adriatic Sea: De Novo Assembly and Bioinformatic Profiling. [PDF]

Int J Mol Sci
Šamanić I, Dželalija M, Bellulovich E, Kalinić H, Jozić S, Ordulj M, Udiković-Kolić N, Maravić A.   +7 more
europepmc   +1 more source