Results 161 to 170 of about 1,239,164 (310)

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Whole-Genome Insights Into Tigecycline-Resistant <i>Klebsiella</i> Spp. Harboring Colistin Resistance Gene From Food Animals in Türkiye. [PDF]

Transbound Emerg Dis
Kürekci C, Lu X, Şahin S, Soyer Y, Wang Z, Hammerl JA, Li R.   +6 more
europepmc   +1 more source

Plasmid incompatibility [PDF]

Microbiological Reviews, 1987
openaire   +2 more sources

plasmid

, 2014
Citation: 'plasmid' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04689 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Mechanistic insights into plasmid transfer inhibition in Enterobacterales by nucleoside analogues. [PDF]

NPJ Antimicrob Resist
Alav I, Ashraf A, Pordelkhaki P, Buckner MMC.   +3 more
europepmc   +1 more source

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Expanded-spectrum β-Lactamase and Plasmid-mediated Quinolone Resistance

Emerging Infectious Diseases, 2007
Laurent Poirel, Laura Villa, Alessia Bertini, Johann D. Pitout, Patrice Nordmann, Alessandra Carattoli   +5 more
doaj   +1 more source

Occurrence of oxazolidinone resistance genes in enterococci, staphylococci, and Mammaliicoccus sciuri from swine slaughterhouse wastewater, Italy. [PDF]

World J Microbiol Biotechnol
Massacci FR, Simoni S, Albini E, Nigro ME, Russo E, D'achille G, Paoletti C, Morroni G, Mingoia M, Zhu Y, Zhang W, Vignaroli C, Magistrali CF, Giovanetti E, Brenciani A.   +14 more
europepmc   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source