Results 231 to 240 of about 1,390,499 (412)

Method for the isolation of the replication region of a bacterial replicon: construction of a mini-F'kn plasmid [PDF]

, 1976
Michael Lovett, Donald R. Helinski
openalex   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

Advanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll, Marc‐Joseph Antonini, Taylor M. Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas Paniagua, Ethan J. Frey, Ye Ji Kim, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, B. Jill Venton, Polina Anikeeva   +16 more
wiley   +1 more source

Thermosensitive Production of Their Transfer Systems by Group S Plasmids

, 1975
Vidal Rodríguez–Lemoine, A. E. Jacob, R. W. Hedges, Naomi Datta   +3 more
openalex   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

Advanced Materials, EarlyView.
Base editing using nanoneedles efficiently corrects pathogenic variants in the type VII collagen gene of primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. Nanoneedle editing induces minimal and reversible transcriptional perturbations while restoring the production and secretion of functional type VII collagen.
Salman Ahmad Mustfa, Marija Dimitrievska, Cong Wang, Chenlei Gu, Ningjia Sun, Katarzyna Romańczuk, Pawel Karpinski, Łukasz Łaczmański, John A. McGrath, Joanna Jacków‐Malinowska, Ciro Chiappini   +10 more
wiley   +1 more source

Characterization of a mini-ColC1 plasmid [PDF]

, 1976
Vickers Hershfield, H W Boyer, Louise T. Chow, Donald R. Helinski   +3 more
openalex   +1 more source

Nanopore‐Functionalized Hybrid Lipid‐Block Copolymer Membranes Allow Efficient Single‐Molecule Sampling and Stable Sensing of Human Serum

Advanced Materials, EarlyView.
Biological nanopores are highly promising tools for single‐molecule biosensors, but the fragile supporting lipid membranes is a major bottleneck. An alternative hybrid membrane is presented, comprising phospholipids and block co‐polymers, that can be functionalized by a broad variety of nanopores for single‐molecule sensing.
Edo Vreeker, Fabian Grünewald, Nieck Jordy van der Heide, Andrea Bonini, Siewert J. Marrink, Katarzyna (Kasia) Tych, Giovanni Maglia   +6 more
wiley   +1 more source

Electron microscope heteroduplex studies of sequence relations among bacterial plasmids: identification and mapping of the insertion sequences IS1 and IS2 in F and R plasmids [PDF]

, 1975
S Hu, Eiji Otsubo, Norman Davidson, Heinz Saedler   +3 more
openalex   +1 more source

Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice‐Switching Oligonucleotides

Advanced Materials, EarlyView.
Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu, Hanna M. G. Barriga, Margaret N. Holme, Stefanie Morf, James J. Doutch, Samir EL Andaloussi, Tomas Kjellman, Markus Johnsson, Justas Barauskas, Molly M. Stevens   +9 more
wiley   +1 more source

Ultraviolet light protection, enhancement of ultraviolet light mutagenesis, and mutator effect of plasmid R46 in Salmonella typhimurium [PDF]

, 1976
Kristien Mortelmans, B. A. D. Stocker
openalex   +1 more source