Results 281 to 290 of about 1,085,040 (311)

Trade-offs between phage resistance and conjugative ability shape the ecological and evolutionary response of a multidrug resistance plasmid to plasmid-dependent phage

open access: yes
Cazares D   +11 more
europepmc   +1 more source

Plasmid-encoded tet(X) genes that confer high-level tigecycline resistance in Escherichia coli

open access: yesNature Microbiology, 2019
Tigecycline is one of the last-resort antibiotics to treat complicated infections caused by both multidrug-resistant Gram-negative and Gram-positive bacteria1.
Jian Sun, Chong Chen, Youjun Feng
exaly   +2 more sources

PlasFlow: predicting plasmid sequences in metagenomic data using genome signatures

open access: yesNucleic Acids Research, 2018
Plasmids are mobile genetics elements that play an important role in the environmental adaptation of microorganisms. Although plasmids are usually analyzed in cultured microorganisms, there is a need for methods that allow for the analysis of pools of ...
Pawel S Krawczyk, Andrzej Dziembowski
exaly   +2 more sources
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Role of AcrAB-TolC multidrug efflux pump in drug-resistance acquisition by plasmid transfer

open access: yesScience, 2019
A race against time Clinically relevant antimicrobial resistance is largely spread via plasmids that disperse among bacteria during conjugation. How quickly can a resistance gene be expressed after transfer?
Sophie Nolivos   +2 more
exaly   +2 more sources

Persistence and reversal of plasmid-mediated antibiotic resistance

open access: yesNature Communications, 2017
In the absence of antibiotic-mediated selection, sensitive bacteria are expected to displace their resistant counterparts if resistance genes are costly. However, many resistance genes persist for long periods in the absence of antibiotics.
Allison J Lopatkin   +2 more
exaly   +2 more sources

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