Results 51 to 60 of about 1,502,313 (400)

Expression of Green Fluorescence Protein (GFP) in Zebrafish Muscle through Injection: A Gene Therapy Model [PDF]

, 2008
Expression of the target gene is important for gene therapy. Presently, localized transgenesis is used for gene therapy which can be achieved by a target gene expression. Here, we have reported the plasmid mediated gene therapy to zebrafish model.
C. H. Hsu, C. S. Lin, Chiranjib Chakraborty, Jhen Ru Shih, Z.H. Wen   +4 more
core   +2 more sources

Plasmid-driven clonal expansion of multidrug-resistant monophasic Salmonella Typhimurium in a Global Food Trade Hub

Emerging Microbes and Infections
Shenzhen, a major port city with a heavily imported food supply, offers a critical setting to examine the spread and adaptation of multidrug-resistant Salmonella 1,4,[5],12:i: – (S. 1,4,[5],12:i:-).
Dingjie Huang, Ziqi Wu, Yixiang Jiang, Lulu Hu, Rui Cai, Xi Yang, Chen Du, Shiting Chen, Panpan Yang, Bingchan Guo, Xiaolu Shi, Shuang Wu, Yinghui Li, Zhemin Zhou, Qinghua Hu   +14 more
doaj   +1 more source

Genetic and biochemical analyses of chromosome and plasmid gene homologues encoding ICL and ArCP domains in Vibrioanguillarum strain 775 [PDF]

, 2011
Anguibactin, the siderophore produced by Vibrio anguillarum 775 is synthesized from 2,3-dihydroxybenzoic acid (DHBA), cysteine and hydroxyhistamine via a nonribosomal peptide synthetase (NRPS) mechanism.
AF Alice, AM Gehring, B Schwyn, C Notredame, CG Marshall, DH Figurski, EJ Drake, EL Arnow, F Bolivar, F Rusnak, H Naka, HW Boyer, J Frey, J Sambrook, JF Parsons, JF Staab, JH Crosa, JH Crosa, Jorge H. Crosa, JR Lai, JR Pollack, KA Datsenko, LA Actis, LA Actis, LE Quadri, M Balado, M Di Lorenzo, M Di Lorenzo, M Di Lorenzo, M Hahn, M Jalal, M Stork, MA Walter, Manuela Di Lorenzo, ME Tolmasky, ME Tolmasky, Michiel Stork, MK Wolf, PA Bates, Q Chen, RF Conchas, SF Altschul, TA Keating, TJ Welch   +43 more
core   +2 more sources

Emergence of plasmid stability under non-selective conditions maintains antibiotic resistance

Nature Communications, 2019
Plasmid acquisition is an important mechanism of rapid adaptation and niche expansion in prokaryotes. Positive selection for plasmid-coded functions is a major driver of plasmid evolution, while plasmids that do not confer a selective advantage are ...
Tanita Wein, Nils F. Hülter, I. Mizrahi, Tal Dagan   +3 more
semanticscholar   +1 more source

Characterization of a novel Phietavirus genus bacteriophage and its potential for efficient transfer of modified shuttle plasmids to Staphylococcus aureus strains of different clonal complexes

Microbiology Spectrum
Staphylococcus aureus is a significant human pathogen responsible for various nosocomial and community-acquired infections, leading to considerable morbidity and mortality worldwide. Temperate bacteriophages contribute to its virulence and facilitate the
Łukasz Kałuski, Emil Stefańczyk, Aleksandra Głowacka-Rutkowska, Jan Gawor, Joanna Empel, Monika Orczykowska-Kotyna, Aleksandra Szczypkowska, Karolina Żuchniewicz, Robert Gromadka, Małgorzata Łobocka   +9 more
doaj   +1 more source

KPC-2-Producing Carbapenem-Resistant Klebsiella pneumoniae of the Uncommon ST29 Type Carrying OXA-926, a Novel Narrow-Spectrum OXA β-Lactamase

Frontiers in Microbiology, 2021
We isolated and characterized a carbapenem-resistant Klebsiella pneumoniae (CRKP) clinical strain from blood carrying a novel blaOXA gene, blaOXA–926, and belonging to ST29, an uncommon CRKP type. The strain, 130002, was genome sequenced using both short-
Lina Liu, Yu Feng, Li Wei, Yuling Xiao, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong   +7 more
doaj   +1 more source

A second large plasmid encodes conjugative transfer and antimicrobial resistance in O119:H2 and some typical O111 enteropathogenic \u3ci\u3eEscherichia coli\u3c/i\u3e strains [PDF]

, 2007
A novel and functional conjugative transfer system identified in O119:H2 enteropathogenic Escherichia coli (EPEC) strain MB80 by subtractive hybridization is encoded on a large multidrug resistance plasmid, distinct from the well-described EPEC adherence
Mucci, Tania, Nwaneshiudu, Adaobi I., Okeke, Iruka N., Pickard, Derek J.   +3 more
core   +1 more source

Escherichia coli of sequence type 3835 carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12 [PDF]

, 2015
New Delhi metallo-β-lactamase (NDM) represents a serious challenge for treatment and public health. A carbapenem-resistant Escherichia coli clinical strain WCHEC13-8 was subjected to antimicrobial susceptibility tests, whole genome sequencing and ...
Feng, Y, McNally, A, Wang, X, Xie, Y, Yang, P, Zong, Z   +5 more
core   +1 more source

Plasmid detection and assembly in genomic and metagenomic data sets

Genome Research, 2019
Although plasmids are important for bacterial survival and adaptation, plasmid detection and assembly from genomic, let alone metagenomic, samples remain challenging.
D. Antipov, Mikhail Raiko, A. Lapidus, P. Pevzner   +3 more
semanticscholar   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source