Results 51 to 60 of about 1,449,118 (412)

Evidence that the 36kb plasmid of Brachyspira hyodysenteriae contributes to virulence [PDF]

open access: yes, 2011
Swine dysentery (SD) results from infection of the porcine large intestine with the anaerobic intestinal spirochaete Brachyspira hyodysenteriae. Recently the genome of virulent Australian B. hyodysenteriae strain WA1 was sequenced, and a 36. kilobase (kb)
Bellgard, M.I.   +5 more
core   +2 more sources

Antiparallel plasmid-plasmid pairing may control P1 plasmid replication. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1991
The copy number of the P1 plasmid replicon is stringently controlled, giving only one or two copies per newborn cell. Control is achieved by the action of the copy-control locus incA, which contains nine repeats of the 19-basepair binding site for the plasmid-encoded initiator protein RepA.
Ann L. Abeles, Stuart Austin
openaire   +3 more sources

Noise enhanced persistence in a biochemical regulatory network with feedback control [PDF]

open access: yesPhys. Rev. Lett. 100, 058105 (2008), 2007
We find that discrete noise of inhibiting (signal) molecules can greatly delay the extinction of plasmids in a plasmid replication system: a prototypical biochemical regulatory network. We calculate the probability distribution of the metastable state of the plasmids and show on this example that the reaction rate equations may fail in predicting the ...
arxiv   +1 more source

Determination of plasmid copy number in yeast transformants by means of agarose plugs [PDF]

open access: yes, 1993
The determination of plasmid copy number in Saccharomyces cerevisiaetransformants containing circular or linear plasmids is currently performed with total yeast DNA extracts obtained from cultures grown under selection.
AM Guerrini   +3 more
core   +1 more source

Plasmids in Rhizobia: The Role of Nonsymbiotic Plasmids

open access: yesMolecular Plant-Microbe Interactions, 1996
Peer ...
Mercado-Blanco, Jesús, Toro, Nicolás
openaire   +3 more sources

Predictive Modeling of Non-Viral Gene Transfer [PDF]

open access: yesBiotechnology and Bioengineering, Volume 105, Issue 4, 805-813, (2010), 2010
In non-viral gene delivery, the variance of transgenic expression stems from the low number of plasmids successfully transferred. Here, we experimentally determine Lipofectamine- and PEI-mediated exogenous gene expression distributions from single cell time-lapse analysis.
arxiv   +1 more source

Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations

open access: yeseLife, 2017
CRISPR-Cas provides a barrier to horizontal gene transfer in prokaryotes. It was previously observed that functional CRISPR-Cas systems are absent from multidrug-resistant (MDR) Enterococcus faecalis, which only possess an orphan CRISPR locus, termed ...
Karthik Hullahalli   +2 more
doaj   +1 more source

A Plasmid With Conserved Phage Genes Helps Klebsiella pneumoniae Defend Against the Invasion of Transferable DNA Elements at the Cost of Reduced Virulence

open access: yesFrontiers in Microbiology, 2022
Klebsiella pneumoniae exhibits extensive phenotypic and genetic diversity. Higher plasmid loads in the cell were supposed to play an key role in its genome diversity.
Mufeng Cai   +23 more
doaj   +1 more source

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

open access: yesAnnals of the New York Academy of Sciences, 2019
Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐priority pathogens owing to their high association with mortalities and morbidities.
K. Kopotsa, John Osei Sekyere, N. Mbelle
semanticscholar   +1 more source

Guidelines for the estimation and reporting of plasmid conjugation rates [PDF]

open access: yesarXiv, 2023
Conjugation is a central characteristic of plasmid biology and an important mechanism of horizontal gene transfer in bacteria. However, there is little consensus on how to accurately estimate and report plasmid conjugation rates, in part due to the wide range of available methods.
arxiv  

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