Results 31 to 40 of about 145,569 (114)
Microbiology SpectrumStaphylococcus aureus is a significant human pathogen responsible for various nosocomial and community-acquired infections, leading to considerable morbidity and mortality worldwide. Temperate bacteriophages contribute to its virulence and facilitate the
Łukasz Kałuski +9 more
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Frontiers in Microbiology, 2021 We isolated and characterized a carbapenem-resistant Klebsiella pneumoniae (CRKP) clinical strain from blood carrying a novel blaOXA gene, blaOXA–926, and belonging to ST29, an uncommon CRKP type. The strain, 130002, was genome sequenced using both short-
Lina Liu +7 more
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The role of hosts, plasmids and environment in determining plasmid transfer rates: a meta-analysis [PDF]
, 2019 Plasmids transfer at highly variable rates which spread over 10 orders of magnitude. While rates have been measured for decades and it is known that the rates are affected by biotic and abiotic factors, it is unclear how and to what extent these factors ...
Sheppard, Richard +2 more
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Genetic Insights on Meropenem Resistance Concerning Klebsiella pneumoniae Clinical Isolates
LifeThe transferable genetic elements are associated with the dissemination of virulence determinants amongst Klebsiella pneumoniae. Thus, we assessed the correlated antimicrobial resistance in carbapenem-resistant Klebsiella pneumoniae clinical isolates ...
Fathy M. Elkady +7 more
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A Primary Physiological Role of Toxin/Antitoxin Systems Is Phage Inhibition
Frontiers in Microbiology, 2020 Toxin/antitoxin (TA) systems are present in most prokaryote genomes. Toxins are almost exclusively proteins that reduce metabolism (but do not cause cell death), and antitoxins are either RNA or proteins that counteract the toxin or the RNA that encodes ...
Sooyeon Song, Thomas K. Wood
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First Report of a Methicillin-Resistant, High-Level Mupirocin-Resistant Staphylococcus argenteus
Frontiers in Cellular and Infection Microbiology, 2022 We describe the identification of a methicillin-resistant, high-level mupirocin-resistant Staphylococcus argenteus. The isolate (1801221) was characterized as t6675-ST2250-SCCmecIVc, and whole-genome sequencing revealed that the isolate possessed two ...
Adebayo Osagie Shittu +7 more
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Antibiotic residues and R-plasmid selection: are in vitro methods good models? [PDF]
, 1987 Three clones of E. coli, one of which was harbouring a tetracycline resistance plasmid were inoculated together into the stomach of axenic mice. Without antibiotic selective pressure, the R-Plasmid bearing strain became dominant in the faeces of mice ...
Lumeau, Solange, Corpet, Denis E.
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Isolation and sequencing of the replication region of plasmid pBFp1 isolated from a marine biofilm
, 2004 A 24 kb plasmid, pBFp1, encoding mercury resistance was previously isolated from a marine biofilm. Isolation and sequencing of a 4280 bp DNA fragment containing the plasmid replicon (rep-pBFp1) revealed a putative open reading frame encoding a RepA ...
Bergström, Maria +2 more
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Intramuscular DNA vaccine provides protection in non-human primate and mouse models of SARS-CoV-2
Frontiers in ImmunologyNucleic acid vaccine approaches have proven successful in the context of the SARS-CoV-2 pandemic, however challenges with delivery remain. Here we describe PlaCCine, a DNA-based vaccine platform that utilizes a device- and vector-free chemical delivery ...
Subeena Sood +20 more
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Verfahren zur Herstellung pharmazeutischer Plasmid-DNA [PDF]
, 2008 Voß C. Processes for the production of pharmaceutical grade plasmid DNA. Bielefeld (Germany): Bielefeld University; 2008.Plasmid DNA is currently used in gene therapy and genetic vaccination as a vector system for the delivery of therapeutic genes ...
Voß, Carsten
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