Genotypic analyses of IncHI2 plasmids from enteric bacteria
Incompatibility (Inc) HI2 plasmids are large (typically > 200 kb), transmissible plasmids that encode antimicrobial resistance (AMR), heavy metal resistance (HMR) and disinfectants/biocide resistance (DBR).
Steven L Foley, Mark Hart
exaly +4 more sources
IncHI2 Plasmids Are Predominant in Antibiotic-Resistant Salmonella Isolates [PDF]
The wide usage of antibiotics contributes to the increase in the prevalence of antibiotic-resistant Salmonella. Plasmids play a critical role in horizontal transfer of antibiotic resistance markers in Salmonella.
Xiujuan Zhou, Xianming Shi, Chunlei Shi
exaly +5 more sources
Potential dissemination of IncHI2/IncHI2A plasmids carrying mcr-9.4 complex transposon in chicken-derived Enterobacter hormaechei [PDF]
The escalating global prevalence of antimicrobial resistance(AMR) represents a critical public health challenge, particularly concerning the compromised efficacy of polymyxins—essential therapeutic agents against carbapenem-resistant Gram-negative ...
Panpan Liu +6 more
doaj +2 more sources
During a regular monitoring of antimicrobial resistance in a farrowing farm in Southern China, 117 Escherichia coli isolates were obtained from sows and piglets.
Jian Sun, Ya-Hong Liu, Xiao-Ping Liao
exaly +3 more sources
Understanding the Association of Plasmid Incompatibility Groups With Variable Antimicrobial Resistance Genotypes in Bacteria. [PDF]
Multi‐replicon plasmids, particularly those belonging to the IncF, IncI, and IncH families, act as major vectors of antimicrobial resistance genes. Although no clear association was found between incompatibility groups and specific antibiotic classes, plasmids with more replicons exhibited higher resistance potential, highlighting their role in AMR ...
de Souza HCA +5 more
europepmc +2 more sources
Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent <i>Klebsiella pneumoniae</i> in Swine: Genomic Insights and Functional Validation. [PDF]
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Chen Z +15 more
europepmc +2 more sources
Emergence of transmissible mcr-9.1 plasmids in clinical Cronobacter sakazakii: CRISPR typing unravels phage-driven evolution and high-risk lineage [PDF]
Cronobacter spp. is an important foodborne pathogen that causes serious neonatal infections. The prevalence of the colistin resistance gene mcr-9 in Cronobacter spp.
Haiyan Zeng +7 more
doaj +2 more sources
Antibiotic resistance profiles and genomic analysis of Klebsiella pneumoniae ST15 with mcr-1 gene isolated from mink in China [PDF]
Background Klebsiella pneumoniae (K. pneumoniae) is a zoonotic opportunistic pathogen that can cause pneumonia in minks, significantly impacting the mink breeding industry. In this study, a K.
Na Sun +9 more
doaj +2 more sources
One Health at Risk: Plasmid-Mediated Spread of mcr-1 Across Clinical, Agricultural, and Environmental Ecosystems [PDF]
The global dissemination of plasmid-mediated mcr genes, which confer resistance to the last-resort antibiotic colistin, represents a critical public health challenge driven by the interplay of clinical, agricultural, and environmental factors.
Abdelaziz Touati +5 more
doaj +2 more sources
The aim of our study was to determine complete nucleotide sequence of mcr-1-carrying plasmids from Enterobacterales isolates recovered from domestic and imported raw retailed meat and compare them with plasmids available at the GenBank sequence database.
Marketa Zelendova +23 more
doaj +1 more source

