Genomic and Pathogenic Characterization of an Extensively Drug-Resistant Avian Pathogenic <i>Escherichia coli</i> Strain. [PDF]
Extensively drug‐resistant (XDR) avian pathogenic Escherichia coli (APEC) poses a global threat to poultry and public health. In this study, we isolated an APEC strain, SDLYRA415, from broilers in Shandong, China, during an outbreak with ~20% mortality.
Ni W +6 more
europepmc +2 more sources
A region of the IncHI2 plasmid R478, encoding the phenotypes of tellurite resistance (Te-r), phage inhibition (Phi), and colicin resistance (PacB), was cloned and sequenced. Analysis indicated seven open reading frames (ORFs), whose genes were designated
Whelan, K F, Colleran, E, Taylor, D E
core +5 more sources
Emergence of transmissible mcr-9.1 plasmids in clinical Cronobacter sakazakii: CRISPR typing unravels phage-driven evolution and high-risk lineage [PDF]
Cronobacter spp. is an important foodborne pathogen that causes serious neonatal infections. The prevalence of the colistin resistance gene mcr-9 in Cronobacter spp.
Haiyan Zeng +7 more
doaj +2 more sources
Antibiotic resistance profiles and genomic analysis of Klebsiella pneumoniae ST15 with mcr-1 gene isolated from mink in China [PDF]
Background Klebsiella pneumoniae (K. pneumoniae) is a zoonotic opportunistic pathogen that can cause pneumonia in minks, significantly impacting the mink breeding industry. In this study, a K.
Na Sun +9 more
doaj +2 more sources
The aim of our study was to determine complete nucleotide sequence of mcr-1-carrying plasmids from Enterobacterales isolates recovered from domestic and imported raw retailed meat and compare them with plasmids available at the GenBank sequence database.
Marketa Zelendova +23 more
doaj +1 more source
Colistin is considered as an antibiotic of ‘last resort’ for the treatment of lethal infections caused by carbapenem-resistant Enterobacterales (CRE), dissemination of plasmid-borne colistin resistance gene mcr-1, particularly into CRE, resulting in the ...
Shuang Xia +16 more
doaj +1 more source
Mapping studies and genetic analysis of transfer genes of the multi-resistant IncHI2 plasmid, R478 [PDF]
A bank of transfer-defective Tn7 insertion mutants of the multi-resistant IncHI2 megaplasmid, R478, was generated. Complementation analysis of these mutations identified a large 144-kb transfer-associated region of R478. A 6.8-kb segment from the transfer region was sequenced.
D T, Page, K F, Whelan, E, Colleran
openaire +3 more sources
Spread of oqxAB in Salmonella enterica serotype Typhimurium predominantly by IncHI2 plasmids [PDF]
To investigate the prevalence and genetic environment of the multiresistance gene oqxAB in Salmonella enterica serotype Typhimurium isolated from food-producing animals.In this study, 63 Salmonella enterica serotype Typhimurium isolates were analysed for the presence of plasmid-mediated quinolone resistance determinants and mutations in the quinolone ...
Liang, Li +10 more
openaire +2 more sources
A collection of 177 genomes of Salmonella Typhimurium and its monophasic variant isolated in 2014–2019 from Italian poultry/livestock (n = 165) and foodstuff (n = 12), previously screened for antimicrobial susceptibility and assigned to ST34 and single ...
Elena Lavinia Diaconu +10 more
doaj +1 more source
Silent spread of mobile colistin resistance gene mcr-9.1 on IncHI2 ‘superplasmids’ in clinical carbapenem-resistant Enterobacterales [PDF]
mcr-9.1 is a newly described mobile colistin resistance gene. We have noted its presence in multiple species of carbapenem-resistant Enterobacterales (CRE) from our institution. We aimed to determine the clinical features, genomic context and phenotypic impact of mcr-9.1 carriage in a series of patients between 2010 and 2019.We identified 32 patients ...
Nenad, Macesic +9 more
openaire +2 more sources

