Results 61 to 70 of about 1,946 (157)

Integrated Genomic and Phenotypic Characterization of an Mcr-10.1‐Harboring Multidrug Resistant Escherichia coli Strain From Migratory Birds in China

Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Background: The global rise in antibiotic resistance among multidrug resistant (MDR) Gram‐negative (GN) bacteria has posed significant health challenges, leading to the resurgence of colistin as a key defense against these bacteria. However, the widespread use of colistin has resulted in the rapid emergence of colistin resistance on a global scale. Ten
Ronglei Huang, Xue Ji, Bing Liang, Bowen Jiang, Danhong Wang, Yi Tang, Chengyang Zhang, Ang Zhou, Nan Li, Chongtao Du, Yang Sun, Zongfu Wu   +11 more
wiley   +1 more source

Compensatory evolution of chromosomes and plasmids counteracts the plasmid fitness cost

Ecology and Evolution, Volume 14, Issue 8, August 2024.
In this review, we provide a comprehensive overview of the currently reported mechanisms underlying compensatory evolution on chromosomes and plasmids, elucidate key targets regulating plasmid fitness cost, and discuss future challenges in this field.
Ziyi Liu, Qiuyun Zhao, Chenggang Xu, Houhui Song   +3 more
wiley   +1 more source

Detection and characterization of a clinical Escherichia coli ST3204 strain coproducing NDM-16 and MCR-1 [Corrigendum]

Infection and Drug Resistance, 2019
Li X, Mu X, Zhang P, et al. Infect Drug Resist. 2018;11:1189–1195.On page 1192, Table 2, in sub-column “Incompatibility and size of mcr-1”, the data in fourth NDM-1 gene was IncHI2, ~60 kb but should be IncI2, ~60 kb. The data in second
Li X, Mu X, Zhang P, Zhao D, Ji J, Quan J, Zhu Y, Yu Y   +7 more
doaj  

Detection of Five mcr-9-Carrying Enterobacterales Isolates in Four Czech Hospitals

mSphere, 2020
The aim of this study was to report the characterization of the first mcr-positive Enterobacterales isolated from Czech hospitals. In 2019, one Citrobacter freundii and four Enterobacter isolates were recovered from Czech hospitals.
Ibrahim Bitar, Costas C. Papagiannitsis, Lucie Kraftova, Katerina Chudejova, Vittoria Mattioni Marchetti, Jaroslav Hrabak   +5 more
doaj   +1 more source

Emergence of a bla _NDM-5 Carrying IncHI2/IncHI2A Plasmid in a Multidrug Resistant Clinical ST1431 Escherichia coli Strain. [PDF]

Infect Drug Resist
Carbapenems are the last-resort antibiotics used to treat infections caused by bacterial pathogens. Many bacterial pathogens have evolved to produce NDM carbapenemases to hydrolyze carbapenems, posing a great challenge to public health. In this study, we report a multidrug resistant clinical E. coli strain 673.
Lin X, Lin Z, Chen D, Huang R, Liang H.
europepmc   +4 more sources

Prevalence and molecular epidemiology of carbapenemase‐producing Enterobacterales isolated from dog and cat faeces submitted to veterinary laboratories in the USA

Zoonoses and Public Health, Volume 71, Issue 5, Page 538-548, August 2024.
Abstract Aims To estimate the prevalence of carbapenemase‐producing Enterobacterales (CPE) carriage among pets using faecal specimens submitted to veterinary diagnostic laboratories throughout the US. A secondary aim was to employ whole‐genome sequencing (WGS) to characterize isolates of CPE from companion animals and compare them to publicly available
Jaclyn Dietrich, Tessa E. LeCuyer, G. Kenitra Hendrix, Claire R. Burbick, Megan E. Jacob, Barbara A. Byrne, Karen Olsen, Maria Mitchell, Olgica Ceric, Rachel Lin, Jessica Joneson, Megan Lintner, Alexandra Fox, Diamond McClendon, Trevor Alexander, Kayla Joyce, Melissa Byrd, Jason Clinton, Keith Snipes, Laura Peak, Stephen D. Cole   +20 more
wiley   +1 more source

Molecular characterization of virulence and resistance genes in Salmonella strains isolated from chickens sold at the informal chicken market in Gauteng Province, South Africa

Journal of Food Safety, Volume 44, Issue 2, April 2024.
The study determined the occurrence and molecular characteristics of virulence and antimicrobial resistance genes in Salmonella strains from chickens sampled at the informal market in Gauteng province, South Africa. Human consumers of chickens contaminated with virulent and AMR gene‐carrying Salmonella pose a risk of salmonellosis with therapeutic ...
Thelma M. Mokgophi, Nomakorinte Gcebe, Folorunso Fasina, Abiodun A. Adesiyun   +3 more
wiley   +1 more source

Microbial evolution through horizontal gene transfer by mobile genetic elements

Microbial Biotechnology, Volume 17, Issue 1, January 2024.
This mini‐review explores the behaviour of conjugative plasmids in various environments, discusses recent methodologies for tracking mobile genetic elements (MGE) dynamics, and underscores the importance of understanding horizontal gene transfer (HGT) mechanisms to develop effective strategies against antimicrobial resistance genes (ARGs) dissemination.
Maho Tokuda, Masaki Shintani
wiley   +1 more source

Genome‐Based Molecular Diversity of Extended‐Spectrum β‐Lactamase‐Producing Escherichia coli From Pigeons in China

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
Extended‐spectrum β‐lactamase‐producing Escherichia coli (ESBL‐EC) strains present a significant menace to the well‐being of both animals and humans. However, limited information is available regarding their profiles in pigeons. Using a combination of whole genome sequencing, drug susceptibility testing, and bioinformatics analysis, we examined the ...
Shuangyu Li, Xinshuai Liu, Haoyu Zhao, Yuhua Zhang, Zheng Lu, Juan Wang, Ruichao Li, Peng Xie, Yibin Hu, Caiyuan Zhou, Qian Mao, Leilei Sun, Shanshan Li, Wenhui Wang, Fang Wang, Xinyu Liu, Tiantian Liu, Wei Pan, Chengbao Wang, Linzhu Ren   +19 more
wiley   +1 more source

mcr-1−Harboring Salmonella enterica Serovar Typhimurium Sequence Type 34 in Pigs, China

Emerging Infectious Diseases, 2017
We detected the mcr-1 gene in 21 (14.8%) Salmonella isolates from pigs at slaughter; 19 were serovar Typhimurium sequence type 34. The gene was located on IncHI2-like plasmids that also harbored IncF replicons and lacked a conjugative transfer region ...
Linxian Yi, Jing Wang, Yanling Gao, Yiyun Liu, Yohei Doi, Renjie Wu, Zhenling Zeng, Zisen Liang, Jian-Hua Liu   +8 more
doaj   +1 more source