Results 1 to 10 of about 57,154 (167)
Colistin Resistance in Bacteria: Current Updates on Mechanism of Action and Combating Strategies [PDF]
Canadian Journal of Infectious Diseases and Medical MicrobiologyThe rapid development of colistin-resistant bacteria is the biggest global health issue since colistin is referred to as a ‘last-hope resource’ against life-threatening infections caused by GNB (Gram-negative bacteria). Injudicious and excessive colistin
Indu Singh +4 more
doaj +2 more sources
An Evaluation of Alternative Treatment Strategies in Mitigating Colistin Resistance: Targeting Plasmid Transfer Through the Use of Bambermycin or the Protein Coded by the Mcr‐1 Gene With Antibodies and Streptomycin [PDF]
Veterinary Medicine and ScienceBackground Plasmid mediated antimicrobial resistance continues to be a source of global concern, especially given the limited pipeline of novel antibiotics.
Ibrahim Z. Hassan +2 more
doaj +2 more sources
Frontiers in Microbiology, 2021 Colistin and tigecycline are the last options against carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP). Intersecting resistance determinants have been detected between these antibiotics; however, there is only limited evidence of such ...
Yawei Zhang +7 more
doaj +1 more source
Role of efflux pumps, their inhibitors, and regulators in colistin resistance
Frontiers in Microbiology, 2023 Colistin is highly promising against multidrug-resistant and extensively drug-resistant bacteria clinically. Bacteria are resistant to colistin mainly through mcr and chromosome-mediated lipopolysaccharide (LPS) synthesis-related locus variation. However,
Yinhuan Ding +9 more
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2021 Background: Antimicrobial resistance to colistin, a widely used feed additive for farm animals across the world, has raised public health concern in recent years.
Masaru Usui +6 more
doaj +1 more source
Old drug, new findings: colistin resistance and dependence of [PDF]
Precision and Future Medicine, 2017 Colistin is an old drug, and its use has recently resurged because of increasing antibiotic resistance in gram-negative bacteria such as Acinetobacter baumannii.
Kwan Soo Ko, Yujin Choi, Ji-Young Lee
doaj +1 more source
Emerging Microbes and Infections, 2021 Infections caused by extensively drug-resistant (XDR) Acinetobacter nosocomialis have become a challenging problem. The frequent use of colistin as the last resort drug for XDR bacteria has led to the emergence of colistin-resistant A.
Ya-Sung Yang +10 more
doaj +1 more source
Asian Pacific Journal of Tropical Medicine, 2022 Objective: To find a proper method to assess colistin resistance in multidrug resistant Gram negative bacteria (MDR-GNB) on a routine basis in resource limited settings. Methods: Clinical samples were processed.
Shubham Chauhan +4 more
doaj +1 more source
Colistin Resistance and Management of Drug Resistant Infections
Canadian Journal of Infectious Diseases and Medical Microbiology, 2022 Colistin resistance is a globalized sensible issue because it has been considered a drug of the last-line resort to treat drug-resistant bacterial infections.
Juhi Sharma +3 more
doaj +1 more source
Effect of Different Media on the Bactericidal Activity of Colistin and on the Synergistic Combination With Azidothymidine Against mcr-1-Positive Colistin-Resistant Escherichia coli [PDF]
, 2020 Antimicrobial susceptibility testing (AST) performed according to defined guidelines is important to identify resistance and to predict the clinical success or failure of specific antibiotic therapy.
Coates, A +4 more
core +1 more source