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Colistin Resistance and Management of Drug Resistant Infections
Canadian Journal of Infectious Diseases and Medical Microbiology, 2022 Colistin resistance is a globalized sensible issue because it has been considered a drug of the last-line resort to treat drug-resistant bacterial infections.
Juhi Sharma +3 more
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Journal of Global Antimicrobial Resistance, 2021 Background: Antimicrobial resistance to colistin, a widely used feed additive for farm animals across the world, has raised public health concern in recent years.
Masaru Usui +6 more
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Colistin Resistance in Bacteria: Current Updates on Mechanism of Action and Combating Strategies [PDF]
Canadian Journal of Infectious Diseases and Medical MicrobiologyThe rapid development of colistin-resistant bacteria is the biggest global health issue since colistin is referred to as a ‘last-hope resource’ against life-threatening infections caused by GNB (Gram-negative bacteria). Injudicious and excessive colistin
Indu Singh +4 more
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Frontiers in Microbiology, 2021 Colistin and tigecycline are the last options against carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP). Intersecting resistance determinants have been detected between these antibiotics; however, there is only limited evidence of such ...
Yawei Zhang +7 more
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Role of efflux pumps, their inhibitors, and regulators in colistin resistance
Frontiers in Microbiology, 2023 Colistin is highly promising against multidrug-resistant and extensively drug-resistant bacteria clinically. Bacteria are resistant to colistin mainly through mcr and chromosome-mediated lipopolysaccharide (LPS) synthesis-related locus variation. However,
Yinhuan Ding +9 more
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Old drug, new findings: colistin resistance and dependence of [PDF]
Precision and Future Medicine, 2017 Colistin is an old drug, and its use has recently resurged because of increasing antibiotic resistance in gram-negative bacteria such as Acinetobacter baumannii.
Kwan Soo Ko, Yujin Choi, Ji-Young Lee
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Emerging Microbes and Infections, 2021 Infections caused by extensively drug-resistant (XDR) Acinetobacter nosocomialis have become a challenging problem. The frequent use of colistin as the last resort drug for XDR bacteria has led to the emergence of colistin-resistant A.
Ya-Sung Yang +10 more
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Asian Pacific Journal of Tropical Medicine, 2022 Objective: To find a proper method to assess colistin resistance in multidrug resistant Gram negative bacteria (MDR-GNB) on a routine basis in resource limited settings. Methods: Clinical samples were processed.
Shubham Chauhan +4 more
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A link between pH homeostasis and colistin resistance in bacteria
Scientific Reports, 2021 Colistin resistance is complex and multifactorial. DbcA is an inner membrane protein belonging to the DedA superfamily required for maintaining extreme colistin resistance of Burkholderia thailandensis. The molecular mechanisms behind this remain unclear.
Pradip R. Panta, William T. Doerrler
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Microbiology Spectrum, 2021 Colistin resistance due to the mcr-type genes in Escherichia coli is well characterized. In order to study the resistance mechanism in mcr-negative colistin-resistant E.
Ching-Hsun Wang +4 more
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