Characterization of Mycobacterium tuberculosis heteroresistance by genotyping
International Journal of Mycobacteriology, 2020 Background: Heteroresistance is the coexistence of susceptible and resistant strains in the same individual, considered the preliminary step for total resistance, and can stem from mixed infection or clonal heterogeneity.
Lida Jouca de Assis Figueredo +6 more
doaj +4 more sources
Investigation of Colistin Heteroresistance and Some Factors Affecting Heteroresistance in Carbapenem-Resistant A. baumannii Strains [PDF]
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2017 Introduction: Colistin can be used in patients infected with carbapenem-resistant Acinetobacter baumannii complex (CR-ABC), but recently resistance to colistin and heteroresistance have been reported.
Deniz GAZEL, Müşerref TATMAN OTKUN
doaj +5 more sources
Insight into the Mechanisms and Clinical Relevance of Antifungal Heteroresistance
Journal of FungiAntifungal resistance poses a critical global health threat, particularly in immuno-compromised patients. Beyond the traditional resistance mechanisms rooted in heritable and stable mutations, a distinct phenomenon known as heteroresistance has been ...
Yanyu Su +5 more
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Antibiotic Heteroresistance in Klebsiella pneumoniae
International Journal of Molecular Sciences, 2021 Klebsiella pneumoniae is one of the most common pathogens responsible for infections, including pneumonia, urinary tract infections, and bacteremias. The increasing prevalence of multidrug-resistant K.
Karolina Stojowska-Swędrzyńska +3 more
core +3 more sources
Heteroresistance: a concern of increasing clinical significance? [PDF]
Clinical Microbiology and Infection, 2008 Recent studies have focused on issues related to heteroresistance, including its definition, methods of detection and frequency. Most such studies have reported data concerning infections caused by Staphylococcus aureus, but the clinical significance of ...
Falagas, M.E. +7 more
core +5 more sources
Heteroresistance to penicillin in Streptococcus pneumoniae [PDF]
Proceedings of the National Academy of Sciences, 2007 Heteroresistance to beta-lactam antibiotics has been mainly described for staphylococci, for which it complicates diagnostic procedures and therapeutic success.
Morand, Brigitte, Mühlemann, Kathrin
core +5 more sources
Journal of Medical Microbiology and Infectious Diseases, 2021 Introduction: Heteroresistance is the phenomenon wherein subpopulations of microbes exhibit a range of resistance to an antibiotic and are prevalent in a broad range of microorganisms.
Mohammad Taha Ebrahimi +4 more
doaj +2 more sources
Prevalence and extent of heteroresistance by next generation sequencing of multidrug-resistant tuberculosis. [PDF]
PLoS ONE, 2017 Amplicon-based Next Generation Sequencing (NGS) is an emerging method for Mycobacterium tuberculosis drug susceptibility testing (DST) but has not been well described. We examined 158 clinical multidrug-resistant M.
Darwin J Operario +12 more
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Imipenem heteroresistance but not tolerance in Haemophilus influenzae during chronic lung infection associated with chronic obstructive pulmonary disease [PDF]
Frontiers in Microbiology, 2023 Antibiotic resistance is a major Public Health challenge worldwide. Mechanisms other than resistance are described as contributors to therapeutic failure.
Celia Gil-Campillo +15 more
doaj +2 more sources
Species-dependent in polymyxin B heteroresistance: genomic insights into adaptive evolution in Enterobacteriaceae [PDF]
Annals of Clinical Microbiology and AntimicrobialsBackground Polymyxin heteroresistance poses a growing challenge in antimicrobial resistance management, yet its epidemiological features and molecular basis across different bacterial species and environments remain poorly understood. This study aimed to
Hui Zhang +7 more
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