Results 1 to 10 of about 3,808 (178)

Insight into the Mechanisms and Clinical Relevance of Antifungal Heteroresistance

Journal of Fungi (Basel, Switzerland)
Antifungal resistance poses a critical global health threat, particularly in immuno-compromised patients. Beyond the traditional resistance mechanisms rooted in heritable and stable mutations, a distinct phenomenon known as heteroresistance has been ...
Tianshu Sun, Qiaolian Yi, Yingxing Li
exaly   +6 more sources

Investigation of Colistin Heteroresistance and Some Factors Affecting Heteroresistance in Carbapenem-Resistant A. baumannii Strains [PDF]

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2017
Introduction: Colistin can be used in patients infected with carbapenem-resistant Acinetobacter baumannii complex (CR-ABC), but recently resistance to colistin and heteroresistance have been reported.
Deniz GAZEL, Müşerref TATMAN OTKUN
doaj   +5 more sources

Characterization of Mycobacterium tuberculosis heteroresistance by genotyping

International Journal of Mycobacteriology, 2020
Background: Heteroresistance is the coexistence of susceptible and resistant strains in the same individual, considered the preliminary step for total resistance, and can stem from mixed infection or clonal heterogeneity.
Lida Jouca de Assis Figueredo, Isabela Neves de Almeida, Claudio José Augusto, Valéria Martins Soares, Philip Noel Suffys, Wânia da Silva Carvalho, Silvana Spíndola de Miranda   +6 more
doaj   +4 more sources

MexS mediated heteroresistance of Pseudomonas aeruginosa to ciprofloxacin [PDF]

Frontiers in Microbiology
Bacterial heteroresistance has been increasingly identified as an important phenomenon for many antibiotic/bacterium combinations. However the mechanisms underlying ciprofloxacin heteroresistance in P.
Xiaodan Ma, Xiaodan Ma, Yana Chen, Chenlu Xiao, Chenlu Xiao, Congcong Li, Lizhong Han, Lizhong Han, Chengxi Li, Chengxi Li, Jinjing Ni   +10 more
doaj   +6 more sources

Global trends and research profile of antibiotic heteroresistance: a bibliometric and visual analysis [PDF]

Frontiers in Microbiology
IntroductionAntibiotic heteroresistance challenges clinical treatment, risking adverse outcomes and antimicrobial resistance emergence. This study aims to explore its research status and trends.MethodsWe screened global publications on antibiotic ...
Jie Hou, Jie Hou, Jie Hou, Jie Hou, Chen Peng, Weilin Chen, Liang Peng, Liang Peng, Liang Peng, Ying Ma, Ying Ma, Ying Ma, Mei Kang, Mei Kang, Mei Kang   +14 more
doaj   +3 more sources

Biofilm Formation and the Pore Proteins ompF and ompC Lead to Heteroresistance in Escherichia coli [PDF]

Antibiotics
Escherichia coli (E. coli) is a major pathogen responsible for mastitis and calf diarrhea in dairy cows and has developed heteroresistance (HR) to a wide range of antibiotics.
Jiaojiao Gao, Yating Wu, Xianlan Ma, Xiaowei Xu, Zhijie Zhang, Wei Shao, Nan Zheng, Tongjun Guo, Yankun Zhao   +8 more
doaj   +3 more sources

Heteroresistance to colistin in wild-type Klebsiella pneumoniae isolates from clinical origin

Microbiology Spectrum, 2023
Heteroresistance to colistin can be defined as the presence of resistant subpopulations in an isolate that is susceptible to colistin. The aim of this work was to study heteroresistance in 10 wild-type Klebsiella pneumoniae isolates of clinical origin ...
Teresa Garcia-Martinez, Luis Martinez Martinez, Elena Perez-Nadales   +2 more
exaly   +3 more sources

Polymyxin heteroresistance in <i>Klebsiella oxytoca</i>. [PDF]

J Med Microbiol
Introduction. Antibiotic heteroresistance presents a growing public health concern, as the phenotype is associated with treatment failure and is hard to detect using conventional diagnostic testing. Gap Statement. Heteroresistance in
Ayerakwa EA, Douglas EJA, Larrouy-Maumus G, Edwards AM, Isawumi A.   +4 more
europepmc   +3 more sources

Species-dependent in polymyxin B heteroresistance: genomic insights into adaptive evolution in Enterobacteriaceae [PDF]

Annals of Clinical Microbiology and Antimicrobials
Background Polymyxin heteroresistance poses a growing challenge in antimicrobial resistance management, yet its epidemiological features and molecular basis across different bacterial species and environments remain poorly understood. This study aimed to
Hui Zhang, Linna Xu, Xiaofen Mo, Biao Tang, Junfeng Fan, Tingting Xiao, Qixia Luo, Fen Wan   +7 more
doaj   +2 more sources

Tandem amplification of the umpA allele contributes to ceftazidime-avibactam heteroresistance in clinical carbapenem-resistant Klebsiella pneumoniae isolates [PDF]

Microbiology Spectrum
Ceftazidime-avibactam (CAZ/AVI, CZA) combination has shown promising efficacy against carbapenem-resistant Klebsiella pneumoniae (CRKP); however, several recent studies have reported resistance to CZA in CRKP.
Mengyao Wang, Ying Li, Jia Hu, Yu Zhang, Jing Yu, Feng Li, Yuqiao Han, Yuyuan Li, Tao Song, Yiling Lin, Yang Chen   +10 more
doaj   +2 more sources