Results 11 to 20 of about 2,895 (162)

MexS mediated heteroresistance of Pseudomonas aeruginosa to ciprofloxacin [PDF]

Frontiers in Microbiology
Bacterial heteroresistance has been increasingly identified as an important phenomenon for many antibiotic/bacterium combinations. However the mechanisms underlying ciprofloxacin heteroresistance in P.
Xiaodan Ma, Xiaodan Ma, Yana Chen, Chenlu Xiao, Chenlu Xiao, Congcong Li, Lizhong Han, Lizhong Han, Chengxi Li, Chengxi Li, Jinjing Ni   +10 more
doaj   +5 more sources

Characterization of Mycobacterium tuberculosis heteroresistance by genotyping

International Journal of Mycobacteriology, 2020
Background: Heteroresistance is the coexistence of susceptible and resistant strains in the same individual, considered the preliminary step for total resistance, and can stem from mixed infection or clonal heterogeneity.
Lida Jouca de Assis Figueredo, Isabela Neves de Almeida, Claudio José Augusto, Valéria Martins Soares, Philip Noel Suffys, Wânia da Silva Carvalho, Silvana Spíndola de Miranda   +6 more
doaj   +3 more sources

Investigation of Colistin Heteroresistance and Some Factors Affecting Heteroresistance in Carbapenem-Resistant A. baumannii Strains [PDF]

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2017
Introduction: Colistin can be used in patients infected with carbapenem-resistant Acinetobacter baumannii complex (CR-ABC), but recently resistance to colistin and heteroresistance have been reported.
Deniz GAZEL, Müşerref TATMAN OTKUN
doaj   +3 more sources

Mixed infections and heteroresistance of Mycobacterium tuberculosis among multidrug-resistant tuberculosis in China: a genomic epidemiology study [PDF]

Emerging Microbes and Infections
Mixed infection refers to the presence of multiple Mycobacterium tuberculosis strains within one host, while heteroresistance denotes the coexistence of drug-susceptible and drug-resistant strains or genotypes.
Yanping Liu, Yangyi Zhang, Xiaoyu Lu, Zheyuan Wu, Minjuan Li, Rui Zhang, Yixiao Lu, Renjie Hou, Yating Ji, Qingping Zhang, Qi Jiang, Jing Li, Yuan Jiang, Yunxia Wang, Jianhui Yuan, Howard E. Takiff, Xin Chen, Xin Shen, Chongguang Yang   +18 more
doaj   +2 more sources

Plasmid pHXY0908 confers ciprofloxacin heteroresistance to Salmonella enterica serovar typhimurium ATCC 14028 by regulating efflux pump gene expression [PDF]

BMC Microbiology
Background Salmonella enterica Serovar Typhimurium (S. Typhimurium) is a major global foodborne pathogen. In our previous study, the S. Typhimurium ATCC 14028 strain harboring plasmid pHXY0908 survived at fourfold its ciprofloxacin MIC (MIC0908 = 0.125 ...
Mengyuan Li, Xiaoyin Feng, Qianting Jian, Mou Jing, Xiran Wang, Zehua Cui, Rongmin Zhang, Jian Sun, Yahong Liu, Xiaoping Liao, Xinlei Lian   +10 more
doaj   +2 more sources

Detection of Colistin Heteroresistance in Carbapenem-Resistant <i>Pseudomonas aeruginosa</i> Clinical Isolates in Iran. [PDF]

Int J Microbiol
Background Since antimicrobial resistance is a rising danger and a serious threat to the health of humans, recent studies have revealed that routine tests, such as minimum inhibitory concentration (MIC), are not enough to detect heteroresistance (HR) phenotype (i.e., phenotypic heterogeneity in antibiotic susceptibility in the identical bacterial ...
Rad ZR, Rad ZR, Goudarzi H, Goudarzi M, Pourdehghan P, Kargar M, Shams S, Hashemi A.   +7 more
europepmc   +2 more sources

Detection and Characterization of Colistin Heteroresistance in an Enterobacter cloacae ST48 Strain Isolated From Raw Milk in Algeria. [PDF]

Vet Med Sci
Enterobacter cloacae ST48 isolate from raw cow milk exhibits colistin heteroresistnace profile. Chromosomal gene mutations in mgrB, phoPQ and pmrAB, incude colistin resistance in E. claocea isolate ABSTRACT An Enterobacter cloacae ST48 isolate exhibiting a colistin‐heteroresistant phenotype was obtained from raw cow milk in Algeria.
Tahar S, Abdelaziz T, Safia T, Nabil MM, Diene SM.   +4 more
europepmc   +2 more sources

Insight into the Mechanisms and Clinical Relevance of Antifungal Heteroresistance

Journal of Fungi
Antifungal resistance poses a critical global health threat, particularly in immuno-compromised patients. Beyond the traditional resistance mechanisms rooted in heritable and stable mutations, a distinct phenomenon known as heteroresistance has been ...
Yanyu Su, Yi Li, Qiaolian Yi, Yingchun Xu, Tianshu Sun, Yingxing Li   +5 more
doaj   +3 more sources

Epidemiology, mechanisms, and clinical impact of bacterial heteroresistance

npj Antimicrobials and Resistance
Bacterial heteroresistance, a phenomenon where subpopulations within a bacterial strain exhibit significantly reduced antibiotic susceptibility compared to the main population, poses a major challenge in managing infectious diseases.
Linna Xu, Xiaofen Mo, Hui Zhang, Fen Wan, Qixia Luo, Yonghong Xiao   +5 more
doaj   +3 more sources

Investigation of voriconazole heteroresistance in clinical isolates of Trichosporon asahii from a multicenter study in China [PDF]

Microbiology Spectrum
Heteroresistance refers to the presence of subpopulations within seemingly homogeneous microbial cells that exhibit varying sensitivities to antifungal agents, potentially contributing to treatment failure.
Chenlu Liu, Qiaoying Gao, Yingxing Li, Jinhan Yu, Shuying Yu, Xinfei Chen, Xue Li, Yingchun Xu, Ying Zhao, Lina Guo   +9 more
doaj   +2 more sources