Results 21 to 30 of about 2,895 (162)

Heteroresistance is associated with mutations during low concentration of tigecycline therapy in multiple-resistant Klebsiella pneumoniae [PDF]

Annals of Clinical Microbiology and Antimicrobials
Background Heteroresistance can lead to treatment failure and has brought a rigorous challenge to clinical laboratories for detecting them. The aim of this study was to investigate the potential for tigecycline-susceptible Klebsiella pneumoniae (K ...
Qiaoyu Zhang, Linwen Zheng, Lirong Wen, Shanshan Li, Yuli Nie, Jiansen Chen   +5 more
doaj   +2 more sources

Polymyxin heteroresistance in <i>Klebsiella oxytoca</i>. [PDF]

J Med Microbiol
Introduction. Antibiotic heteroresistance presents a growing public health concern, as the phenotype is associated with treatment failure and is hard to detect using conventional diagnostic testing. Gap Statement. Heteroresistance in
Ayerakwa EA, Douglas EJA, Larrouy-Maumus G, Edwards AM, Isawumi A.   +4 more
europepmc   +3 more sources

Analysis of β-lactams and Carbapenem Heteroresistance in Extra-intestinal Pathogenic Escherichia coli from Blood Samples in Iran

Journal of Medical Microbiology and Infectious Diseases, 2021
Introduction: Heteroresistance is the phenomenon wherein subpopulations of microbes exhibit a range of resistance to an antibiotic and are prevalent in a broad range of microorganisms.
Mohammad Taha Ebrahimi, Mohsen Nazari, Niloofar Mobarezpour, Hamed Afkhami, Sepideh Fereshteh   +4 more
doaj   +1 more source

Antibiotic Heteroresistance in Klebsiella pneumoniae

International Journal of Molecular Sciences, 2021
Klebsiella pneumoniae is one of the most common pathogens responsible for infections, including pneumonia, urinary tract infections, and bacteremias. The increasing prevalence of multidrug-resistant K. pneumoniae was recognized in 2017 by the World Health Organization as a critical public health threat.
Karolina Stojowska-Swędrzyńska, Adrianna Łupkowska, Dorota Kuczyńska-Wiśnik, Ewa Laskowska   +3 more
openaire   +2 more sources

Heteroresistance to clarithromycin and metronidazole in patients with a Helicobacter pylori infection: a systematic review and meta-analysis

Annals of Clinical Microbiology and Antimicrobials, 2022
Background Antimicrobial resistance of H. pylori can lead to treatment failure. Importantly, several studies have reported on heteroresistance, i.e. the presence of resistant and susceptible H. pylori populations in the same sample and/or a difference in
Ebrahim Kouhsari, Nourkhoda Sadeghifard, Arezoo Khadiv, Hojjat Sayadi, Taghi Amiriani, Sobhan Ghafourian, Hassan Valadbeigi, Marcela Krutova   +7 more
doaj   +1 more source

Prevalence and extent of heteroresistance by next generation sequencing of multidrug-resistant tuberculosis. [PDF]

PLoS ONE, 2017
Amplicon-based Next Generation Sequencing (NGS) is an emerging method for Mycobacterium tuberculosis drug susceptibility testing (DST) but has not been well described. We examined 158 clinical multidrug-resistant M.
Darwin J Operario, Alexander F Koeppel, Stephen D Turner, Yongde Bao, Suporn Pholwat, Sayera Banu, Suporn Foongladda, Stellah Mpagama, Jean Gratz, Oleg Ogarkov, Svetlana Zhadova, Scott K Heysell, Eric R Houpt   +12 more
doaj   +1 more source

Ceftaroline-Heteroresistant Staphylococcus aureus [PDF]

Antimicrobial Agents and Chemotherapy, 2014
ABSTRACT Heteroresistance refers to the presence, within a large population of antimicrobial-susceptible microorganisms, of subpopulations with lesser susceptibilities. Ceftaroline is a novel cephalosporin with activity against methicillin-resistant Staphylococcus aureus (MRSA).
Stephanie N, Saravolatz, Hayley, Martin, Joan, Pawlak, Leonard B, Johnson, Louis D, Saravolatz   +4 more
openaire   +2 more sources

Heteroresistance to penicillin in Streptococcus pneumoniae [PDF]

Proceedings of the National Academy of Sciences, 2007
Heteroresistance to β-lactam antibiotics has been mainly described for staphylococci, for which it complicates diagnostic procedures and therapeutic success. This study investigated whether heteroresistance to penicillin exists in Streptococcus pneumoniae .
Morand, Brigitte, Mühlemann, Kathrin
openaire   +4 more sources

Detection of Heteroresistant Mycobacterium tuberculosis by Pyrosequencing [PDF]

Journal of Clinical Microbiology, 2013
ABSTRACT The ability of pyrosequencing to detect a resistant minority population of a heteroresistant Mycobacterium tuberculosis strain was investigated by performing a titration study. A mutant signal was noted only when the proportion of mutant DNA in the DNA target was 35 to 50%, showing that the ...
Anna, Engström, Sven, Hoffner, Pontus, Juréen   +2 more
openaire   +2 more sources

Heteroresistance to Fluconazole and Voriconazole in Cryptococcus neoformans [PDF]

Antimicrobial Agents and Chemotherapy, 1999
ABSTRACT Cryptococcus neoformans isolates that exhibited unusual patterns of resistance to fluconazole and voriconazole were isolated from seven isolates from two different geographical regions: one isolate from an Israeli non-AIDS patient and six serial isolates from an Italian AIDS patient who had suffered six ...
Mondon P., Petter R., Amalfitano G., LUZZATI, ROBERTO, Concia E., Polacheck I., Kwon Chung K. J.   +6 more
openaire   +4 more sources