Results 21 to 30 of about 3,479 (180)

Deletions of recombination genes impair tandem amplification and reshape heteroresistance mechanisms in Escherichia coli [PDF]

mBio
Heteroresistance is a transient resistance phenotype characterized by the presence of small subpopulations of bacterial cells with elevated antibiotic resistance within a susceptible main population.
Sheida Heidarian, Karin Hjort, Hervé Nicoloff, Dan I. Andersson   +3 more
doaj   +2 more sources

Mixed infections and heteroresistance of Mycobacterium tuberculosis among multidrug-resistant tuberculosis in China: a genomic epidemiology study [PDF]

Emerging Microbes and Infections
Mixed infection refers to the presence of multiple Mycobacterium tuberculosis strains within one host, while heteroresistance denotes the coexistence of drug-susceptible and drug-resistant strains or genotypes.
Yanping Liu, Yangyi Zhang, Xiaoyu Lu, Zheyuan Wu, Minjuan Li, Rui Zhang, Yixiao Lu, Renjie Hou, Yating Ji, Qingping Zhang, Qi Jiang, Jing Li, Yuan Jiang, Yunxia Wang, Jianhui Yuan, Howard E. Takiff, Xin Chen, Xin Shen, Chongguang Yang   +18 more
doaj   +2 more sources

Vancomycin heteroresistance in Staphylococcus haemolyticus: elusive phenotype

Future Science OA, 2021
Aim: To determine the presence of vancomycin heteroresistance in Staphylococcus haemolyticus. Materials & methods: A total of 48 rifampicin-resistant S. haemolyticus isolates from bloodstream infections were included.
Shalini Anandan, Balaji Veeraraghavan, Dhanalakshmi Solaimalai, Anushree Amladi, Hariharan Triplicane Dwarakanathan, Yamuna Devi Bathavatchalam   +5 more
core   +4 more sources

Detection of Colistin Heteroresistance in Carbapenem-Resistant <i>Pseudomonas aeruginosa</i> Clinical Isolates in Iran. [PDF]

Int J Microbiol
Background Since antimicrobial resistance is a rising danger and a serious threat to the health of humans, recent studies have revealed that routine tests, such as minimum inhibitory concentration (MIC), are not enough to detect heteroresistance (HR) phenotype (i.e., phenotypic heterogeneity in antibiotic susceptibility in the identical bacterial ...
Rad ZR, Rad ZR, Goudarzi H, Goudarzi M, Pourdehghan P, Kargar M, Shams S, Hashemi A.   +7 more
europepmc   +2 more sources

Plasmid pHXY0908 confers ciprofloxacin heteroresistance to Salmonella enterica serovar typhimurium ATCC 14028 by regulating efflux pump gene expression [PDF]

BMC Microbiology
Background Salmonella enterica Serovar Typhimurium (S. Typhimurium) is a major global foodborne pathogen. In our previous study, the S. Typhimurium ATCC 14028 strain harboring plasmid pHXY0908 survived at fourfold its ciprofloxacin MIC (MIC0908 = 0.125 ...
Mengyuan Li, Xiaoyin Feng, Qianting Jian, Mou Jing, Xiran Wang, Zehua Cui, Rongmin Zhang, Jian Sun, Yahong Liu, Xiaoping Liao, Xinlei Lian   +10 more
doaj   +2 more sources

Multicenter Study of Colistin Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae Strains in China

Microbiology Spectrum, 2023
Colistin has been considered a last-line option for the treatment of infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP). Heterogeneous resistance to colistin leads to unexplained clinical colistin treatment failure for CRKP. Our study
Yuesong Weng, Tao Wang, Bin Huang, Hua Yu, Wei Jia, Bin Shan, Fen Qu, Yiwei Tang, Liang Chen, Hong Du   +9 more
doaj   +2 more sources

MexS mediated heteroresistance of Pseudomonas aeruginosa to ciprofloxacin [PDF]

Frontiers in Microbiology
Bacterial heteroresistance has been increasingly identified as an important phenomenon for many antibiotic/bacterium combinations. However the mechanisms underlying ciprofloxacin heteroresistance in P.
Xiaodan Ma, Xiaodan Ma, Yana Chen, Chenlu Xiao, Chenlu Xiao, Congcong Li, Lizhong Han, Lizhong Han, Chengxi Li, Chengxi Li, Jinjing Ni   +10 more
doaj   +2 more sources

Heteroresistance to Colistin in Clinical Isolates of Klebsiella pneumoniae Producing OXA-48 [PDF]

Antibiotics, 2023
Heteroresistance to colistin can be defined as the presence of resistant subpopulations in an isolate that is susceptible to this antibiotic. Colistin resistance in Gram-negative bacteria is more frequently related to chromosomal mutations and insertions.
Irene Sánchez-León, Teresa García-Martínez, Seydina M. Diene, Elena Pérez-Nadales, Luis Martínez-Martínez, Jean-Marc Rolain   +5 more
doaj   +2 more sources

Impact of heteroresistance on treatment outcomes of people with drug-resistant TB [PDF]

IJTLD Open
BACKGROUND: Poor treatment outcomes among people with drug-resistant TB (DR-TB) are a major concern. Heteroresistance (presence of susceptible and resistant Mycobacterium tuberculosis in the same sample) has been identified in some people with TB, but ...
R. Crowder, M. Kato-Maeda, B. Schwem, A. dela Tonga, D.M. Geocaniga-Gaviola, E. Lopez, C.L. Valdez, A.R. Lim, N. Hunat, A.G. Sedusta, C.A. Sacopon, G.A.M. Atienza, E. Bulag, D. Lim, J. Bascuña, K. Shah, R.P. Basillio, C.A. Berger, M.C.D.P. Lopez, S. Sen, C. Allender, M. Folkerts, U. Karaoz, E. Brodie, S. Mitarai, A.M.C. Garfin, M.C. Ama, D.M. Engelthaler, A. Cattamanchi, R. Destura   +29 more
doaj   +2 more sources

Epidemiology of cryptococcal meningitis and fluconazole heteroresistance in Cryptococcus neoformans isolates from a teaching hospital in southwestern China

Microbiology Spectrum
Cryptococcal meningitis (CM), a common and serious opportunistic infection mostly caused by Cryptococcus neoformans, is primarily treated with fluconazole.
Yunfei Huang, Yongqi Zhang, Shuangshuang Yang, Hongling Lu, Hanbing Yu, Xingyue Wang, Xiaojiong Jia, Dijiao Tang, Linhong Wu, Shifeng Huang, Ping Yang   +10 more
doaj   +2 more sources