Results 31 to 40 of about 2,895 (162)
Detection of Pyrazinamide Heteroresistance in Mycobacterium tuberculosis
Antimicrobial Agents and Chemotherapy, 2021 Heteroresistance is defined as the coexistence of both susceptible and resistant bacteria in a bacterial population. Previously published data show that it may occur in 9 to 57% of Mycobacterium tuberculosis isolates for various drugs.
Jim Werngren +4 more
openaire +2 more sources
Heteroresistance to Cephalosporins and Penicillins in Acinetobacter baumannii [PDF]
Journal of Clinical Microbiology, 2012 ABSTRACT Heteroresistance to antimicrobial agents may affect susceptibility test results and therapeutic success. In this study, we investigated heteroresistance to cephalosporins and penicillins in Acinetobacter baumannii , a major pathogen causing nosocomial infections. Two A. baumannii
Kuei-Hsiang, Hung +4 more
openaire +2 more sources
Heteroresistance: a concern of increasing clinical significance? [PDF]
Clinical Microbiology and Infection, 2008 Recent studies have focused on issues related to heteroresistance, including its definition, methods of detection and frequency. Most such studies have reported data concerning infections caused by Staphylococcus aureus, but the clinical significance of heteroresistance is unclear. Six studies have described infections caused by S.
Falagas, M.E. +3 more
openaire +3 more sources
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundAntimicrobial susceptibility testing (AST) plays a vital role in anti-Helicobacter pylori treatment, but the traditional AST method has difficulty detecting heteroresistance, which may cause an increased prevalence of resistant strains and ...
You-hua Wang +7 more
doaj +1 more source
Heteroresistance of Cryptococcus gattii to Fluconazole [PDF]
Antimicrobial Agents and Chemotherapy, 2010 ABSTRACT We analyzed 71 clinical and environmental Cryptococcus gattii strains that had been isolated before or after the advent of azole antifungals to determine their level of heteroresistance to fluconazole (LHF). All strains of C.
A, Varma, K J, Kwon-Chung
openaire +2 more sources
Bacterial Cooperation Leads to Heteroresistance
DEStech Transactions on Computer Science and Engineering, 2018 By challenging E. coli with sublethal norfloxacin for 10 days, Henry Lee and James Collins suggests the bacterial altruism leads to the population-wide resistance. By detailedly analyzing experiment data, we suggest that bacterial cooperation leads to population-wide resistance under norfloxacin pressure and simultaneously propose the bacteria shield ...
Xu, Shilian, Yang, Jiaru, Yin, Chong
openaire +3 more sources
mBio, 2016 Candida glabrata causes persistent infections in patients treated with fluconazole and often acquires resistance following exposure to the drug. Here we found that clinical strains of C.
Ronen Ben-Ami +7 more
doaj +1 more source
Frontiers in Microbiology, 2023 Antibiotic resistance is a major Public Health challenge worldwide. Mechanisms other than resistance are described as contributors to therapeutic failure.
Celia Gil-Campillo +15 more
doaj +1 more source
Heteroresistance to Vancomycin in Enterococcus faecium [PDF]
Journal of Clinical Microbiology, 2001 ABSTRACT This study presents the first report of vancomycin heteroresistance in an Enterococcus faecium isolate from a patient. The original isolate was susceptible in vitro to vancomycin. E-tests showed growth of subcolonies in a zone of inhibition with a vancomycin MIC of >256 μg/ml.
M R, Alam +6 more
openaire +2 more sources
Reaction Kinetic Models of Antibiotic Heteroresistance [PDF]
International Journal of Molecular Sciences, 2019 Bacterial heteroresistance (i.e., the co-existence of several subpopulations with different antibiotic susceptibilities) can delay the clearance of bacteria even with long antibiotic exposure. Some proposed mechanisms have been successfully described with mathematical models of drug-target binding where the mechanism’s downstream of drug-target binding
Antal Martinecz +3 more
openaire +3 more sources