Colistin Dependency among Colistin-Heteroresistant Acinetobacter baumannii Isolates [PDF]
Colistin dependent (CD) isolates are dependent on colistin for optimal growth. Here we aimed to systematically determine the emergence of CD among colistin-heteroresistant carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. We also examined the phenotypic characteristics of CD and the evolution of CD strains to overt resistance. Additionally,
Hadas Kon +6 more
openaire +3 more sources
Polymyxins including polymyxin B and colistin (polymyxin E) are considered the last resort for treating infections caused by carbapenem-resistant gram-negative bacteria.
Yifan Wang +7 more
doaj +1 more source
EPIDEMIOLOGY OF VIRAL GASTROENTERITIS IN IRAN [PDF]
Viruses are prominent causative agents of acute gastroenteritis in children
Jalilvand, Somayeh. +3 more
core +1 more source
Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitro [PDF]
Multi-drug strategies have been attempted to prolong the efficacy of existing antibiotics, but with limited success. Here we show that the evolution of multi-drug-resistant Escherichia coli can be manipulated in vitro by administering pairs of ...
Cronin, Leroy +5 more
core +1 more source
Heteroresistance to Fluconazole and Voriconazole in Cryptococcus neoformans [PDF]
ABSTRACT Cryptococcus neoformans isolates that exhibited unusual patterns of resistance to fluconazole and voriconazole were isolated from seven isolates from two different geographical regions: one isolate from an Israeli non-AIDS patient and six serial isolates from an Italian AIDS patient who had suffered six ...
Mondon P. +6 more
openaire +4 more sources
The highly dynamic nature of bacterial heteroresistance impairs its clinical detection
Bacterial populations can show heteroresistance, where an antibiotic resistant subpopulation is part of a susceptible one. Pereira et al. show in Escherichia coli and Salmonella enterica that disk diffusion, a common antibiotic susceptibility test ...
Cátia Pereira +4 more
doaj +1 more source
A consensus statement on empiric therapy for suspected gram-positive infections in surgical patients [PDF]
15Background: Multidrug resistance among gram-positive pathogens in tertiary and other care centers is common. A systematic decision pathway to help select empiric antibiotic therapy for suspected gram-positive postsurgical infections is presented.
core +1 more source
Development of a SimpleProbe real-Time PCR Assay for rapid detection and identification of the US novel urethrotropic clade of Neisseria meningitidis ST-11 (US_NmUC) [PDF]
Urethritis, or inflammation of the urethra, is one of the most common reasons men seek clinical care. Sexually transmitted pathogens including Neisseria gonorrhoeae are responsible for over half of the symptomatic urethritis cases in U.S. men.
Ermel, Aaron +4 more
core +1 more source
Resolving colistin resistance and heteroresistance in Enterobacter species
Abstract Enterobacter cloacae complex (ECC) represent globally important nosocomial pathogens. A three-year study of ECC in Germany identified Enterobacter xiangfangensis as the most common species (65.5%) detected, a result replicated by examining a global pool of 3246 isolates.
Doijad, Swapnil Prakash +44 more
openaire +5 more sources
Treatment of gram - positive infections in critically ill patients [PDF]
Gram-positive bacteria to include methicillin-resistant Staphylococcus aureus (MRSA), methicillin-susceptible Staphylococcus aureus (MSSA), and enterococci, to include vancomycin-resistant enterococci (VRE), display a remarkable array of resistance and ...
Cristina Vazquez-Guillamet +1 more
core +2 more sources

