Results 61 to 70 of about 2,895 (162)

Oxidative Treatment for Reducing Persistent Populations of Escherichia coli Under Amoxicillin and Gentamicin Pressure

Journal of Biophotonics, Volume 19, Issue 3, March 2026.
Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa, Maria Vitória S. Pereira, Vanderlei S. Bagnato, Kate C. Blanco   +3 more
wiley   +1 more source

Colistin heteroresistance in carbapenemase-producing Klebsiella pneumoniae [PDF]

Journal of Antimicrobial Chemotherapy, 2011
Sir, Klebsiella pneumoniae is an important pathogen that causes severe and life-threatening infections. Most isolates demonstrate resistance to various antimicrobial agents. Carbapenems have been widely used to treat serious infections with multidrug-resistant K. pneumoniae.
Georgios, Meletis, Egki, Tzampaz, Effrosyni, Sianou, Ioannis, Tzavaras, Danai, Sofianou   +4 more
openaire   +2 more sources

Emerging Frontiers in Clinical Mycology: Innovations, Insights, and Impacts

Mycoses, Volume 69, Issue 1, January 2026.
ABSTRACT The Mycoses Study Group Education and Research Consortium (MSGERC)—a group comprising clinicians, researchers, patients, and industry partners—meets every 2 years to review the most significant challenges facing the clinical mycology community and plan research, education, and advocacy strategies to prevent fungal infections and improve ...
A. Apostolopoulou, A. G. Stewart, H. Yoon, J. M. Steinbrink, D. Z. P. Friedman, L. Ostrosky‐Zeichner, I. S. Schwartz, on behalf of the Mycoses Study Group Education and Research Consortium (MSGERC)   +7 more
wiley   +1 more source

Fluoroquinolone heteroresistance, antimicrobial tolerance, and lethality enhancement

Frontiers in Cellular and Infection Microbiology, 2022
With tuberculosis, the emergence of fluoroquinolone resistance erodes the ability of treatment to interrupt the progression of MDR-TB to XDR-TB. One way to reduce the emergence of resistance is to identify heteroresistant infections in which subpopulations of resistant mutants are likely to expand and make the infections fully resistant: treatment ...
Amit Singh, Amit Singh, Xilin Zhao, Xilin Zhao, Karl Drlica   +4 more
openaire   +3 more sources

Mutants with heteroresistance to amphotericin B and fluconazole in Candida [PDF]

Brazilian Journal of Microbiology, 2009
Several studies have reported the occurrence of infections caused by Candida yeasts as well as the increasing prevalence of non albicans species. The aim of the present work is focused on the obtaining of heteroresistance to amphotericin B and fluconazole in Candida species using two distinct methodologies: selection and induction.
Claudino, A.L.R., Peixoto Junior, R.F., Melhem, M.S.C., Szeszs, M.W., Lyon, J.P., Chavasco, J.K., Franco, M.C.   +6 more
openaire   +4 more sources

Impact of heteroresistance on treatment outcomes of people with drug-resistant TB

IJTLD Open
BACKGROUND: Poor treatment outcomes among people with drug-resistant TB (DR-TB) are a major concern. Heteroresistance (presence of susceptible and resistant Mycobacterium tuberculosis in the same sample) has been identified in some people with TB, but ...
R. Crowder, M. Kato-Maeda, B. Schwem, A. dela Tonga, D.M. Geocaniga-Gaviola, E. Lopez, C.L. Valdez, A.R. Lim, N. Hunat, A.G. Sedusta, C.A. Sacopon, G.A.M. Atienza, E. Bulag, D. Lim, J. Bascuña, K. Shah, R.P. Basillio, C.A. Berger, M.C.D.P. Lopez, S. Sen, C. Allender, M. Folkerts, U. Karaoz, E. Brodie, S. Mitarai, A.M.C. Garfin, M.C. Ama, D.M. Engelthaler, A. Cattamanchi, R. Destura   +29 more
doaj   +1 more source

Methods to Evaluate Colistin Heteroresistance in Acinetobacter baumannii [PDF]

, 2019
The nosocomial pathogen Acinetobacter baumannii is a growing threat to public health due to its increasing resistance to antibiotics including the last-line polymyxin, colistin. Heteroresistance to colistin has been described in A. baumannii, wherein a resistant subpopulation of cells coexisting with a majority susceptible subpopulation actively grows ...
Edgar X, Sherman, Jessie E, Wozniak, David S, Weiss   +2 more
openaire   +2 more sources

Mechanisms of heteroresistance in methicillin-resistant Staphylococcus aureus [PDF]

Antimicrobial Agents and Chemotherapy, 1994
Characteristic for methicillin-resistant (Mcr) staphylococci is the heterogeneous expression of the intrinsic methicillin resistance. The majority of the cells express resistance to low concentrations of methicillin, and a minority of the cells express resistance to much higher concentrations.
Ryffel C, Strässle A, Kayser FH, Berger-Bächi B   +3 more
openaire   +3 more sources

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 23: Suitability of taxonomic units notified to EFSA until September 2025

EFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The qualified presumption of safety (QPS) process was developed to provide a harmonised safety assessment approach to support EFSA Scientific Panels and Units. The QPS approach assesses the taxonomic identity, body of relevant knowledge and safety of microorganisms intentionally added to the food and feed chain.
EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Marianne Chemaly, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Fulvio Barizzone, Justine Dastouet, Nadya Doyle, Sandra Correia, Lieve Herman   +28 more
wiley   +1 more source

Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli

Journal of Antimicrobial Chemotherapy, 2020
AbstractObjectivesTo explore the effect of combining defects in DNA repair systems with the presence of fosfomycin-resistant mechanisms to explain the mechanisms underlying fosfomycin heteroresistance phenotypes in Enterobacteriaceae.Materials and methodsWe used 11 clinical Escherichia coli isolates together with isogenic single-gene deletion mutants ...
Fernando Docobo-Pérez, Alvaro Pascual, Jesús Rodríguez-Baño, Jesús Blázquez, Belen de Gregorio-Iaria, Jose Manuel Rodríguez-Martínez, Miriam Ortiz-Padilla, Inés Portillo-Calderón   +7 more
openaire   +5 more sources