Results 81 to 90 of about 3,968 (183)
Fluoroquinolone heteroresistance, antimicrobial tolerance, and lethality enhancement
Frontiers in Cellular and Infection Microbiology, 2022 With tuberculosis, the emergence of fluoroquinolone resistance erodes the ability of treatment to interrupt the progression of MDR-TB to XDR-TB. One way to reduce the emergence of resistance is to identify heteroresistant infections in which subpopulations of resistant mutants are likely to expand and make the infections fully resistant: treatment ...
Amit Singh +4 more
openaire +3 more sources
Journal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.Antifungal resistance in tropical mycoses is an increasingly important component of the global antimicrobial resistance crisis, particularly in endemic regions where diagnostic capacity, therapeutic options, and surveillance systems are limited. This review synthesizes clinical, environmental, and genomic evidence on resistance in major endemic and ...
Meral Miraloglu
wiley +1 more source
Helicobacter, Volume 31, Issue 4, July/August 2026.ABSTRACT Background/Aims Since the 2020 Korean guidelines for Helicobacter pylori treatment, clarithromycin resistance rates have risen from 17.8% to 33.3%, dual‐priming oligonucleotide‐based polymerase chain reaction (DPO‐PCR)‐based tailored therapy has been adopted, and P‐CABs have become available.
Chang Seok Bang +14 more
wiley +1 more source
Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus
Photochemistry and Photobiology, Volume 102, Issue 4, Page 924-933, July/August 2026.Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira +3 more
wiley +1 more source
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source
MicrobiologyOpen, Volume 15, Issue 2, April 2026.Oral biofilms from healthy and periodontitis patients harbor diverse bacteria, including aerobes and obligate anaerobes. Using selective media with tetracycline or ciprofloxacin, 495 strains (106 species) were isolated. Resistance was common—32.9% to ciprofloxacin, 15.2% to tetracycline, 0.6% to ampicillin—highlighting the oral cavity as a reservoir ...
Marietta Wolf +9 more
wiley +1 more source
Methods to Evaluate Colistin Heteroresistance in Acinetobacter baumannii [PDF]
, 2019 The nosocomial pathogen Acinetobacter baumannii is a growing threat to public health due to its increasing resistance to antibiotics including the last-line polymyxin, colistin. Heteroresistance to colistin has been described in A. baumannii, wherein a resistant subpopulation of cells coexisting with a majority susceptible subpopulation actively grows ...
Edgar X, Sherman +2 more
openaire +2 more sources
Surface Plasmon Resonance‐based Biosensing Towards the Detection of Multidrug‐Resistant Tuberculosis
Advanced Photonics Research, Volume 7, Issue 3, March 2026.This study presents the detection of multidrug‐resistant tuberculosis (MDR‐TB) gene targets (InhA, KatG, and RpoB) and their mutations using a surface plasmon resonance (SPR)‐based biosensing platform to monitor target binding on functionalized sensor chips.
Sipho H. Chauke +6 more
wiley +1 more source
Journal of Biophotonics, Volume 19, Issue 3, March 2026.Photodynamic inactivation (PDI) with methylene blue and 660 nm LED enhances antibiotic killing of bacteria, accelerating time‐kill kinetics and reducing the MDK99 compared to antibiotics alone. SEM confirms effective cellular damage, demonstrating that PDI potentiates amoxicillin and gentamicin against tolerant bacterial populations. ABSTRACT Bacterial
Bruna C. Correa +3 more
wiley +1 more source
Emerging Frontiers in Clinical Mycology: Innovations, Insights, and Impacts
Mycoses, Volume 69, Issue 1, January 2026.ABSTRACT The Mycoses Study Group Education and Research Consortium (MSGERC)—a group comprising clinicians, researchers, patients, and industry partners—meets every 2 years to review the most significant challenges facing the clinical mycology community and plan research, education, and advocacy strategies to prevent fungal infections and improve ...
A. Apostolopoulou +7 more
wiley +1 more source