Results 91 to 100 of about 3,479 (180)

Real‐Time Assessment of H. pylori Infection to Guide Molecular Antibiotic Resistance Testing: A Combined Endoscopy‐Gastric Juice Analysis Approach

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 3, Page 465-471, February 2025.
Endoscopy combined with intraprocedural gastric juice analysis is highly accurate for Helicobacter pylori detection and, in case of a positive finding, can selectively direct to antibiotic susceptibility testing. Genotypic susceptibility testing using gastric aspirate accurately detects H. pylori resistance to clarithromycin and levofloxacin, with test
Riccardo Vasapolli, Florent Ailloud, Beate Spießberger, Peter Malfertheiner, Sebastian Suerbaum, Christian Schulz   +5 more
wiley   +1 more source

A birth–death model to understand bacterial antimicrobial heteroresistance from time-kill curves

15 pages, 2 tables, 4 figures.-- Under a Creative Commons licenseAntimicrobial heteroresistance refers to the presence of different subpopulations with heterogeneous antimicrobial responses within the same bacterial isolate, so they show reduced ...
Martínez-López, Nerea, Vilas Fernández, Carlos, García, Miriam R.   +2 more
core   +1 more source

Outsmarting Nightmare: Drug Resistance in Acinetobacter baumannii

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.
Acinetobacter baumannii is a critical nosocomial pathogen recognized by the WHO as a top‐priority threat due to its extensive drug resistance, particularly in carbapenem‐resistant Acinetobacter baumannii (CRAB) strains. According to recent CDC reports, CRAB is one of the most urgent causes of hospital‐acquired infections, driving longer hospital stays,
Annepu Praveen, Amjuri Sinduja, Mukesh Kumar Yadav, Divakar Sharma, Amit Singh, Satabdi Datta Choudhury   +5 more
wiley   +1 more source

Contribution of hypermutation to fosfomycin heteroresistance in Escherichia coli

Journal of Antimicrobial Chemotherapy, 2020
AbstractObjectivesTo explore the effect of combining defects in DNA repair systems with the presence of fosfomycin-resistant mechanisms to explain the mechanisms underlying fosfomycin heteroresistance phenotypes in Enterobacteriaceae.Materials and methodsWe used 11 clinical Escherichia coli isolates together with isogenic single-gene deletion mutants ...
Fernando Docobo-Pérez, Alvaro Pascual, Jesús Rodríguez-Baño, Jesús Blázquez, Belen de Gregorio-Iaria, Jose Manuel Rodríguez-Martínez, Miriam Ortiz-Padilla, Inés Portillo-Calderón   +7 more
openaire   +5 more sources

Characterization of fosfomycin heteroresistance among multidrug-resistant Escherichia coli isolates from hospitalized patients in Rio de Janeiro, Brazil

Journal of Global Antimicrobial Resistance, 2020
Objectives: Urinary tract infections (UTIs) caused by multidrug-resistant Escherichia coli have become a major medical concern. Old antibiotics such as fosfomycin have become an alternative therapeutic option due to their effectiveness and, as a result ...
Ana Carolina da C. Campos, Nathália L. Andrade, Natacha Couto, Nico T. Mutters, Marjon de Vos, Ana Cláudia de P. Rosa, Paulo V. Damasco, Jerome R. Lo Ten Foe, Alex W. Friedrich, Monika A. Chlebowicz-Flissikowska, John W.A. Rossen   +10 more
doaj   +1 more source

Revisiting the Metallo‐β‐Lactamase–Mediated Antibiotic Resistance: Exploring Novel Mechanisms and Therapeutic Strategies

International Journal of Microbiology, Volume 2025, Issue 1, 2025.
β‐Lactam resistance is one of the major health concerns today, primarily due to enzymes called β‐lactamases. Metallo‐β‐lactamases (MβLs) can cleave a wide range of β‐lactam antibiotics, including carbapenems. These enzymes require zinc (Zn) ions to function and can be inhibited by conventional β‐lactamase inhibitors.
Jahanvi Saini, Silvi Gautam, Divakar Sharma, Ankit Khanduri, Divya Venugopal, Guilherme Dilarri   +5 more
wiley   +1 more source

Bioactive Compounds and Amino Acids From Sweet and Southern Wormwood (Artemisia spp.): Extraction, Characterization, and Antimicrobial Activity Against Opportunistic Pathogens

Journal of Food Biochemistry, Volume 2025, Issue 1, 2025.
This study was designed to recover bioactive compounds, including artemisinin, phenolics, tannins, and amino acids (AAs), from the aerial parts of Artemisia annua L. (sweet wormwood) and Artemisia abrotanum L. (southern wormwood) using ultrasound‐assisted extraction (UAE).
Evita Kaleja, Vitalijs Radenkovs, Daiga Galina, Karina Juhnevica-Radenkova, Inta Krasnova, Anda Valdovska, Anupama Bose   +6 more
wiley   +1 more source

In vitro Activity and Heteroresistance of Omadacycline Against Clinical Staphylococcus aureus Isolates From China Reveal the Impact of Omadacycline Susceptibility by Branched-Chain Amino Acid Transport System II Carrier Protein, Na/Pi Cotransporter Family Protein, and Fibronectin-Binding Protein

Frontiers in Microbiology, 2019
Omadacycline (Omad), a new tetracycline (Tet)-class broad-spectrum aminomethylcycline, has been reported to exhibit excellent potency against Gram-positive bacteria, including Staphylococcus aureus and Enterococci.
Bing Bai, Bing Bai, Zhiwei Lin, Zhiwei Lin, Zhangya Pu, Guangjian Xu, Guangjian Xu, Fan Zhang, Fan Zhang, Zhong Chen, Zhong Chen, Xiang Sun, Jinxin Zheng, Peiyu Li, Peiyu Li, Qiwen Deng, Qiwen Deng, Zhijian Yu, Zhijian Yu   +18 more
doaj   +1 more source

Study of the Equine Methicillin‐Resistant Staphylococcus aureus Bacterium With a High Ability to Form Biofilms and Changes in Its Properties Under the Influence of Farnesol

Veterinary Medicine International, Volume 2025, Issue 1, 2025.
In developed countries, given the prevalence of methicillin‐resistant Staphylococcus aureus (MRSA), therapeutic options for treating such infections have become limited. In developing countries and Russia, little is known about resistance to antibiotics for St. aureus in veterinary medicine.
Nadezhda Sachivkina, Diana Kondrateva, Olga Kuznetsova, Ekaterina Neborak, Alfia Ibragimova, Abdugani Abdurasulov, Rakhima Muratova, Kursantbek Attokurov, Elmurat Obdunov, Lipi Buch   +9 more
wiley   +1 more source

Heteroresistance and clinical outcomes: knowledge gaps

The Lancet Microbe
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Leanza, Gabriele Maria, Murri, Rita, Sanguinetti, Maurizio, Torti, Carlo   +3 more
openaire   +3 more sources