Results 91 to 100 of about 5,136 (212)

Impact of heteroresistance on treatment outcomes of people with drug-resistant TB

IJTLD Open
BACKGROUND: Poor treatment outcomes among people with drug-resistant TB (DR-TB) are a major concern. Heteroresistance (presence of susceptible and resistant Mycobacterium tuberculosis in the same sample) has been identified in some people with TB, but ...
R. Crowder, M. Kato-Maeda, B. Schwem, A. dela Tonga, D.M. Geocaniga-Gaviola, E. Lopez, C.L. Valdez, A.R. Lim, N. Hunat, A.G. Sedusta, C.A. Sacopon, G.A.M. Atienza, E. Bulag, D. Lim, J. Bascuña, K. Shah, R.P. Basillio, C.A. Berger, M.C.D.P. Lopez, S. Sen, C. Allender, M. Folkerts, U. Karaoz, E. Brodie, S. Mitarai, A.M.C. Garfin, M.C. Ama, D.M. Engelthaler, A. Cattamanchi, R. Destura   +29 more
doaj   +1 more source

Impact of time to appropriate therapy on mortality in patients with vancomycin-intermediate Staphylococcus aureus infection [PDF]

, 2016
Despite the increasing incidence of vancomycin-intermediate Staphylococcus aureus (VISA) infections, few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in VISA patients.
Burnham, Carey-Ann D, Burnham, Jason P, Kollef, Marin H, Warren, David K   +3 more
core   +2 more sources

Helicobacter pylori Infection in Children Versus Adults, Differences in Management Guidelines: Risks and Benefits of Treatment in Childhood

Helicobacter, Volume 30, Issue 4, July/August 2025.
ABSTRACT Helicobacter pylori infection in children and adults differs in several aspects such as the natural history, prevalence, the clinical presentations and complications, antibiotic resistance rates, treatment options, and the success rates of treatment.
Matjaž Homan, Zrinjka Mišak, Francis Megraud, Michal Kori   +3 more
wiley   +1 more source

Methods to Evaluate Colistin Heteroresistance in Acinetobacter baumannii [PDF]

, 2019
The nosocomial pathogen Acinetobacter baumannii is a growing threat to public health due to its increasing resistance to antibiotics including the last-line polymyxin, colistin. Heteroresistance to colistin has been described in A. baumannii, wherein a resistant subpopulation of cells coexisting with a majority susceptible subpopulation actively grows ...
Edgar X, Sherman, Jessie E, Wozniak, David S, Weiss   +2 more
openaire   +2 more sources

Decreased susceptibility to vancomycin and other mechanisms of resistance to antibiotics in Staphylococcus epidermidis as a therapeutic problem in hospital treatment

Scientific Reports, 2023
Multidrug-resistant coagulase-negative staphylococci represent a real therapeutic challenge. The aim of the study was to emphasize the importance of heteroresistance to vancomycin presence in methicillin-resistant strains of S. epidermidis.
Magdalena Szemraj, Paulina Glajzner, Monika Sienkiewicz   +2 more
doaj   +1 more source

An in vitro evaluation of the efficacy of tedizolid: implications for the treatment of skin and soft tissue infections [PDF]

, 2018
Skin and soft tissue infections (SSTI) are among the most commonly occurring infections and evidence suggests that these are increasing world-wide.
Aleryan, Muna, Delpech, Pierre, Gemmell, Curtis, Jones, Brian, Lang, Susan   +4 more
core   +2 more sources

Real‐Time PCR Helicobacter pylori Test in Comparison With Culture and Histology for Helicobacter pylori Detection and Identification of Resistance to Clarithromycin: A Single‐Center Real‐Life Study

Helicobacter, Volume 30, Issue 2, March/April 2025.
ABSTRACT Background In our center, RT‐PCR was integrated as a routine method to diagnose Helicobacter pylori due to its higher availability after COVID‐19 pandemics. The objective of this study was to assess the feasibility and performance of systematically performed RT‐PCR for H.
Kateryna Priadko, Sophie‐Anne Gibaud, Amaury Druet, Louise Galmiche, Francis Megraud, Stéphane Corvec, Tamara Matysiak‐Budnik   +6 more
wiley   +1 more source

Performance of the Genotype MTBDRPlus resistance patternSamara, Russian Federation [PDF]

, 2009
Background. Russia is a high tuberculosis (TB) burden country with a high prevalence of multidrug resistant tuberculosis (MDRTB). Molecular assays for detection of MDRTB on clinical specimens are not widely available in Russia. Results.
Vladyslav Nikolayevskyy, Yanina Balabanova, Tatyana Simak, Nadezhda Malomanova, Ivan Fedorin, Francis Drobniewski, FA Drobniewski, RA Atun, A Telenti, S Ramaswamy, MH Hazbon, M Zhang, P Jureen, T Kocagoz, TJ Brown, D Hillemann, C Piersimoni, P Miotto, D Hillemann, J Makinen, P Miotto, M Barnard, F Drobniewski, OS Toungoussova, A Kruuner, E Tortoli, M Garrigo, MM de Oliveira, VV Nikolayevskyy, D Garcia de Viedma, V Nikolayevsky, MV Afanas'ev, OS Toungoussova, MY Lipin, H Rinder, GC Baldeviano-Vidalon   +35 more
core   +3 more sources

Real‐Time Assessment of H. pylori Infection to Guide Molecular Antibiotic Resistance Testing: A Combined Endoscopy‐Gastric Juice Analysis Approach

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 3, Page 465-471, February 2025.
Endoscopy combined with intraprocedural gastric juice analysis is highly accurate for Helicobacter pylori detection and, in case of a positive finding, can selectively direct to antibiotic susceptibility testing. Genotypic susceptibility testing using gastric aspirate accurately detects H. pylori resistance to clarithromycin and levofloxacin, with test
Riccardo Vasapolli, Florent Ailloud, Beate Spießberger, Peter Malfertheiner, Sebastian Suerbaum, Christian Schulz   +5 more
wiley   +1 more source

Comparison of methods for detection of plasmid-mediated and chromosomally encoded colistin resistance in Enterobacteriaceae [PDF]

, 2017
Objectives: Because of the emergence of plasmid-mediated (mcr-1 and mcr-2 genes) and chromosomally encoded colistin resistance, reliable methods for detecting colistin resistance/susceptibility in routine laboratories are required.
Dubois, Véronique, Jayol, Aurélie, Lehours, Philippe, Nordmann, Patrice, Poirel, Laurent   +4 more
core