Results 41 to 50 of about 3,968 (183)

Polymyxin heteroresistance in <i>Klebsiella oxytoca</i>. [PDF]

J Med Microbiol
Introduction. Antibiotic heteroresistance presents a growing public health concern, as the phenotype is associated with treatment failure and is hard to detect using conventional diagnostic testing. Gap Statement. Heteroresistance in
Ayerakwa EA, Douglas EJA, Larrouy-Maumus G, Edwards AM, Isawumi A.   +4 more
europepmc   +3 more sources

Detection of Heteroresistant Mycobacterium tuberculosis by Pyrosequencing [PDF]

Journal of Clinical Microbiology, 2013
ABSTRACT The ability of pyrosequencing to detect a resistant minority population of a heteroresistant Mycobacterium tuberculosis strain was investigated by performing a titration study. A mutant signal was noted only when the proportion of mutant DNA in the DNA target was 35 to 50%, showing that the ...
Anna, Engström, Sven, Hoffner, Pontus, Juréen   +2 more
openaire   +2 more sources

Heteroresistance to Cephalosporins and Penicillins in Acinetobacter baumannii [PDF]

Journal of Clinical Microbiology, 2012
ABSTRACT Heteroresistance to antimicrobial agents may affect susceptibility test results and therapeutic success. In this study, we investigated heteroresistance to cephalosporins and penicillins in Acinetobacter baumannii , a major pathogen causing nosocomial infections. Two A. baumannii
Kuei-Hsiang, Hung, Ming-Cheng, Wang, Ay-Huey, Huang, Jing-Jou, Yan, Jiunn-Jong, Wu   +4 more
openaire   +2 more sources

Heteroresistance to Fluconazole and Voriconazole in Cryptococcus neoformans [PDF]

Antimicrobial Agents and Chemotherapy, 1999
ABSTRACT Cryptococcus neoformans isolates that exhibited unusual patterns of resistance to fluconazole and voriconazole were isolated from seven isolates from two different geographical regions: one isolate from an Israeli non-AIDS patient and six serial isolates from an Italian AIDS patient who had suffered six ...
Mondon P., Petter R., Amalfitano G., LUZZATI, ROBERTO, Concia E., Polacheck I., Kwon Chung K. J.   +6 more
openaire   +4 more sources

Detection of Pyrazinamide Heteroresistance in Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2021
Heteroresistance is defined as the coexistence of both susceptible and resistant bacteria in a bacterial population. Previously published data show that it may occur in 9 to 57% of Mycobacterium tuberculosis isolates for various drugs.
Jim Werngren, Mikael Mansjö, Mikaela Glader, Sven Hoffner, Lina Davies Forsman   +4 more
openaire   +2 more sources

Bacterial Cooperation Leads to Heteroresistance

DEStech Transactions on Computer Science and Engineering, 2018
By challenging E. coli with sublethal norfloxacin for 10 days, Henry Lee and James Collins suggests the bacterial altruism leads to the population-wide resistance. By detailedly analyzing experiment data, we suggest that bacterial cooperation leads to population-wide resistance under norfloxacin pressure and simultaneously propose the bacteria shield ...
Xu, Shilian, Yang, Jiaru, Yin, Chong
openaire   +3 more sources

An Investigation of Colistin Heteroresistance in <i>Klebsiella pneumoniae</i> Isolates in Iran. [PDF]

Biomed Res Int
Background According to the World Health Organization 2024 bacterial priority pathogens list, carbapenem‐resistant Enterobacterales (CRE) were listed among the critical priority pathogens. Heteroresistance (i.e., a bacterial isolate that appears susceptible but harbors resistant subpopulations) represents a challenge in traditional laboratory testing ...
Rad ZR, Rad ZR, Goudarzi H, Goudarzi M, Javidi M, Sharahi JY, Kargar M, Hashemi A.   +7 more
europepmc   +2 more sources

Heteroresistance to Vancomycin in Enterococcus faecium [PDF]

Journal of Clinical Microbiology, 2001
ABSTRACT This study presents the first report of vancomycin heteroresistance in an Enterococcus faecium isolate from a patient. The original isolate was susceptible in vitro to vancomycin. E-tests showed growth of subcolonies in a zone of inhibition with a vancomycin MIC of >256 μg/ml.
M R, Alam, S, Donabedian, W, Brown, J, Gordon, J W, Chow, M J, Zervos, E, Hershberger   +6 more
openaire   +2 more sources

Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among Candida glabrata Clinical Strains Associated with In Vivo Persistence

mBio, 2016
Candida glabrata causes persistent infections in patients treated with fluconazole and often acquires resistance following exposure to the drug. Here we found that clinical strains of C.
Ronen Ben-Ami, Offer Zimmerman, Talya Finn, Sharon Amit, Anna Novikov, Noa Wertheimer, Mor Lurie-Weinberger, Judith Berman   +7 more
doaj   +1 more source

Heteroresistance of Cryptococcus gattii to Fluconazole [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT We analyzed 71 clinical and environmental Cryptococcus gattii strains that had been isolated before or after the advent of azole antifungals to determine their level of heteroresistance to fluconazole (LHF). All strains of C.
A, Varma, K J, Kwon-Chung
openaire   +2 more sources