Results 11 to 20 of about 2,218,812 (219)
Colistin Resistance and Management of Drug Resistant Infections
Canadian Journal of Infectious Diseases and Medical Microbiology, 2022 Colistin resistance is a globalized sensible issue because it has been considered a drug of the last-line resort to treat drug-resistant bacterial infections.
Juhi Sharma +3 more
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Journal of Global Antimicrobial Resistance, 2021 Background: Antimicrobial resistance to colistin, a widely used feed additive for farm animals across the world, has raised public health concern in recent years.
Masaru Usui +6 more
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Colistin Resistance in Bacteria: Current Updates on Mechanism of Action and Combating Strategies [PDF]
Canadian Journal of Infectious Diseases and Medical MicrobiologyThe rapid development of colistin-resistant bacteria is the biggest global health issue since colistin is referred to as a ‘last-hope resource’ against life-threatening infections caused by GNB (Gram-negative bacteria). Injudicious and excessive colistin
Indu Singh +4 more
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Old drug, new findings: colistin resistance and dependence of [PDF]
Precision and Future Medicine, 2017 Colistin is an old drug, and its use has recently resurged because of increasing antibiotic resistance in gram-negative bacteria such as Acinetobacter baumannii.
Kwan Soo Ko, Yujin Choi, Ji-Young Lee
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Comparative in vivo evaluation of colistin resistance determinants in Escherichia coli clone ST131Research in context [PDF]
EBioMedicineSummary: Background: Colistin is a last-resort antimicrobial for multidrug-resistant (MDR) Gram-negative infections. Health risks associated with colistin resistance are commonly inferred from resistance phenotypes, despite limited in vivo evidence ...
Toyotaka Sato +18 more
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MCR: modern colistin resistance [PDF]
European Journal of Clinical Microbiology & Infectious Diseases, 2016 Recently, plasmid-mediated and, therefore, transferable bacterial polymyxin resistance was discovered in strains from both humans and animals. Such a trait may widely spread geographically, while simultaneously crossing microbial species barriers. This may ultimately render the "last resort" polymyxin antibiotics therapeutically useless.
Caniaux I +4 more
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An overview of colistin resistance, mobilized colistin resistance genes dissemination, global responses, and the alternatives to colistin: A review [PDF]
Veterinary World, 2019 Colistin, also known as polymyxin E, is an antimicrobial agent that is effective against a variety of Gram-negative bacilli, especially the Enterobacteriaceae family. Recently, the wide dissemination of colistin-resistance has brought strong attention to the scientific society because of its importance as the last resort for the treatment of carbapenem-
Mohammad H. Gharaibeh +1 more
openaire +5 more sources
Adaptive colistin resistance dynamics in mcr-9-positive and -negative Enterobacterales following low-level colistin exposure [PDF]
Microbiology SpectrumThe mcr-9 gene has been reported across different sources and was recognized as a potential contributor to increased minimum inhibitory concentrations after colistin exposure. This study aimed to determine the prevalence of intestinal carriage of the mcr-
Eva Smelikova +4 more
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Deciphering MCR-2 Colistin Resistance [PDF]
mBio, 2017 ABSTRACT Antibiotic resistance is a prevalent problem in public health worldwide. In general, the carbapenem β-lactam antibiotics are considered a final resort against lethal infections by multidrug-resistant bacteria. Colistin is a cationic polypeptide antibiotic and acts as the last line of defense for treatment of carbapenem ...
Jian Sun +11 more
openaire +4 more sources
The History of Colistin Resistance Mechanisms in Bacteria: Progress and Challenges
Microorganisms, 2021 Since 2015, the discovery of colistin resistance genes has been limited to the characterization of new mobile colistin resistance (mcr) gene variants. However, given the complexity of the mechanisms involved, there are many colistin-resistant bacterial ...
Mouna Hamel +2 more
doaj +2 more sources