Results 31 to 40 of about 2,218,812 (219)
Presence of Colistin- and Tigecycline-Resistant Klebsiella pneumoniae ST29 in Municipal Wastewater Influents in Japan [PDF]
, 2021 The aim of this study was to investigate the presence of colistin- and/or tigecycline-resistant Klebsiella spp. in influents from four wastewater treatment plants (WWTPs), which partly reflect the gut microbiome of human populations.
Nagano, Yukiko +8 more
core +1 more source
International Journal of Antimicrobial Agents, 2022 The plasmid-mediated bacterial colistin-resistant gene, mcr, is of global concern in clinical healthcare. However, there are few reports of surveillance for mcr in Japan. The aim of this study was to assess the prevalence of colistin resistance by identifying nine mcr genes in extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae and ...
Yasuhide Kawamoto +12 more
openaire +2 more sources
A link between pH homeostasis and colistin resistance in bacteria
Scientific Reports, 2021 Colistin resistance is complex and multifactorial. DbcA is an inner membrane protein belonging to the DedA superfamily required for maintaining extreme colistin resistance of Burkholderia thailandensis. The molecular mechanisms behind this remain unclear.
Pradip R. Panta, William T. Doerrler
doaj +1 more source
mSphere, 2020 Infections by multidrug-resistant Gram-negative bacteria are increasingly common, prompting the renewed interest in the use of colistin. Colistin specifically targets Gram-negative bacteria by interacting with the anionic lipid A moieties of ...
Axel B. Janssen +6 more
doaj +1 more source
Microbiology Spectrum, 2021 Colistin resistance due to the mcr-type genes in Escherichia coli is well characterized. In order to study the resistance mechanism in mcr-negative colistin-resistant E.
Ching-Hsun Wang +4 more
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2020 Colistin is a 'last-line' antibiotic used to treat multidrug-resistant Gram-negative bacteria, but colistin resistance has emerged. Colistin normally binds to the lipid A moiety on the bacterial outer membrane, where it then destroys the bacterial membrane.
Kaitlin S. Witherell +4 more
openaire +3 more sources
, 2022 Background: A collection of human-epidemiologically unrelated S. enterica strains collected over a 3-year period (2016 to 2018) in Italy by the national surveillance Enter-Net Italia was analysed.
Claudia Lucarelli +9 more
core +1 more source
Transcriptomic analysis of colistin-susceptible and colistin-resistant isolates identifies genes associated with colistin resistance in Acinetobacter baumannii [PDF]
Clinical Microbiology and Infection, 2015 The emergence of colistin-resistant Acinetobacter baumannii is concerning, as colistin is often regarded as the last option for treating multidrug-resistant (MDR) A. baumannii infections. Using mRNA sequencing, we compared whole transcriptomes of colistin-susceptible and colistin-resistant A.
Park, Y.K., Lee, J.-Y., Ko, K.S.
openaire +2 more sources
Mobile colistin resistance (mcr) genes and recent developments in colistin resistance detection
Letters in Applied Microbiology, 2023 Abstract The peptide antibiotic colistin has been reserved as a last resort antibiotic treatment option for cases where other antibiotics including carbapenems have failed. Recent emergence of colistin resistance and discovery of mobile colistin resistance (mcr) genes, which encode the cell wall modifying phosphoethanolamine transferase ...
Divya Lakshmanan +3 more
openaire +2 more sources
Antibiotics, 2022 Colistin is a last-line antibiotic against Gram-negative pathogens. However, the emergence of colistin resistance has substantially reduced the clinical effectiveness of colistin. In this study, synergy between colistin and capric acid was examined against twenty-one Gram-negative bacterial isolates (four colistin-susceptible and seventeen colistin ...
Yi-Yun Liu +8 more
openaire +3 more sources