The role of pmrCAB genes in colistin-resistant Acinetobacter baumannii
Scientific Reports, 2022 The progressively increasing antimicrobial-resistant Acinetobacter baumannii infections have enforced the use of colistin as the last option for therapy, resulting in the colistin resistance evolution. This work aimed to study the pmrCAB expression in A.
Shaimaa Mohamed Seleim +3 more
doaj +1 more source
An overview of colistin resistance, mobilized colistin resistance genes dissemination, global responses, and the alternatives to colistin: A review [PDF]
Veterinary World, 2019 Colistin, also known as polymyxin E, is an antimicrobial agent that is effective against a variety of Gram-negative bacilli, especially the Enterobacteriaceae family. Recently, the wide dissemination of colistin-resistance has brought strong attention to the scientific society because of its importance as the last resort for the treatment of carbapenem-
Mohammad H. Gharaibeh +1 more
openaire +3 more sources
Antimicrobial Agents and Chemotherapy, 2023 The emergence of multidrug-resistant Pseudomonas aeruginosa infections has urged the need to find new strategies, such as the use of combinations of antibiotics. Among these, the combination of colistin with other antibiotics has been studied.
Eva Armengol +7 more
openaire +3 more sources
Clonal expansion of colistin-resistant Acinetobacter baumannii isolates in Cape Town, South Africa
International Journal of Infectious Diseases, 2020 Objectives: To describe colistin-resistant Acinetobacter baumannii isolates in Cape Town, South Africa. Methods: A. baumannii isolates identified on Vitek 2 Advanced Expert System were collected from Tygerberg Hospital referral laboratory between 2016 ...
Yolandi Snyman +5 more
doaj +1 more source
Open conversion after aortic endograft infection. Caused by colistin-resistant, carbapenemase-producing Klebsiella pneumoniae [PDF]
, 2016 A 62-year-old man presented with fever, abdominal pain, and malaise 13 months after emergency endovascular aortic repair. Computed tomographic angiograms showed a periprosthetic fluid and gas collection, so infection was diagnosed. Open conversion was
Capoccia, Laura +5 more
core +1 more source
Infectious Microbes & Diseases, 2019 . The increasing prevalence of resistance to the last-resort antibiotics carbapenems is leading to increasing difficulties in treating infections caused by multidrug-resistant carbapenem-resistant Gram-negative bacteria such as Klebsiella pneumoniae. The
Björn Berglund, Stijn van der Veen
doaj +1 more source
Increasing proportion of carbapenemase-producing Enterobacteriaceae and emergence of a MCR-1 producer through a multicentric study among hospital-based and private laboratories in Belgium from September to November 2015 [PDF]
, 2017 Carbapenemase-producing Enterobacteriaceae (CPE) strains have been increasingly reported in Belgium. We aimed to determine the proportion of CPE among Enterobacteriaceae isolated from hospitalised patients and community outpatients in Belgium in 2015 ...
Bauraing, Caroline +8 more
core +1 more source
In vivo therapeutic efficacy of frog skin-derived peptides against Pseudomonas aeruginosa-induced pulmonary infection [PDF]
, 2017 Pseudomonas aeruginosa is an opportunistic and frequently drug-resistant pulmonary pathogen especially in cystic fibrosis sufferers. Recently, the frog skin-derived antimicrobial peptide (AMP) Esc(1-21) and its diastereomer Esc(1-21)-1c were found to ...
Chen, Chen +2 more
core +1 more source
Advanced Science, EarlyView.This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen +8 more
wiley +1 more source
Second-Generation Tryptamine Derivatives Potently Sensitize Colistin Resistant Bacteria to Colistin [PDF]
ACS Medicinal Chemistry Letters, 2019 Antibiotic resistance has significantly increased since the beginning of the 21st century. Currently, the polymyxin colistin is typically viewed as the antibiotic of last resort for the treatment of multidrug resistant Gram-negative bacterial infections.
Bradley M. Minrovic +6 more
openaire +2 more sources